Evidence map›Paper›PMID 34150657›Full record

ArticleFrontiers in oncology2021

An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure.

Isabella Guardamagna, Leonardo Lonati, Monica Savio, Lucia A Stivala, Andrea Ottolenghi, Giorgio Baiocco

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of Different Enzymes in HInternational journal of molecular sciences · 2025
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  8. Delphinidin-3-rutinoside from Blackcurrant Berries (Molecules (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Isabella GuardamagnaLaboratory of Radiation Biophysics and Radiobiology, Department of Physics, University of Pavia, Pavia, Italy.
Leonardo LonatiLaboratory of Radiation Biophysics and Radiobiology, Department of Physics, University of Pavia, Pavia, Italy.
Monica SavioImmunology and General Pathology Unit, Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Lucia A StivalaImmunology and General Pathology Unit, Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Andrea OttolenghiLaboratory of Radiation Biophysics and Radiobiology, Department of Physics, University of Pavia, Pavia, Italy.
Giorgio BaioccoLaboratory of Radiation Biophysics and Radiobiology, Department of Physics, University of Pavia, Pavia, Italy.
University of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is among the three top cancer types for incidence and the second in terms of mortality, usually managed with surgery, chemotherapy and radiotherapy. In particular, radiotherapeutic concepts are crucial for the management of advanced rectal cancer, but patients' survival remains poor, despite advances in treatment modalities. The use of well-characterized

Indexed as

Caco-2cell cyclecell survival and deathG2/M arrestgenomic aberrationsionizing radiationmetalloproteases

Identifiers

PMID34150657
PMCPMC8209426
OpenAlexW3166347285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.