Evidence map›Paper›PMID 34150627›Full record

ArticleFrontiers in oncology2021

A Poliovirus Receptor (CD155)-Related Risk Signature Predicts the Prognosis of Bladder Cancer.

Cong Luo, Wenrui Ye, Jiao Hu, Belaydi Othmane, Huihuang Li, Jinbo Chen, Xiongbing Zu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cong LuoDepartment of Urology, Xiangya Hospital, Central South University (CSU), Changsha, China.
Wenrui YeClinical Medicine Eight-year Program, Xiangya Medical School of Central South University, Changsha, China.
Jiao HuDepartment of Urology, Xiangya Hospital, Central South University (CSU), Changsha, China.
Belaydi OthmaneDepartment of Urology, Xiangya Hospital, Central South University (CSU), Changsha, China.
Huihuang LiDepartment of Urology, Xiangya Hospital, Central South University (CSU), Changsha, China.
Jinbo ChenDepartment of Urology, Xiangya Hospital, Central South University (CSU), Changsha, China.
Xiongbing ZuDepartment of Urology, Xiangya Hospital, Central South University (CSU), Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBladder cancer is an aggressive and heterogeneous disease associated with high morbidity and mortality. And poliovirus receptor (

methodsA total of 797 patients from TCGA and GEO databases were employed in our study, in which 285 cases were set as the training cohort and 512 were defined as the validation cohort. Our own Xiangya cohort with 57 samples was also used for the validation. Survival differences were evaluated by Kaplan-Meier analysis between groups. The immune infiltration was evaluated by ESTIMATE, TIMER, and CIBERSORT algorithms. The risk signature was constructed by LASSO Cox regression analysis. And a nomogram model was generated subsequent to the multivariate Cox proportional hazards analysis to predict 3- and 5-year survival of patients with bladder cancer.

results

conclusionOur study revealed that

Indexed as

bladder cancerCD155immune infiltrationnomogrampoliovirus receptorprognosisrisk signature

Identifiers

PMID34150627
PMCPMC8210672
OpenAlexW3169557734

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.