ReviewAnesthesiology and pain medicine2020
Carpal Tunnel Release Surgery- A Systematic Review of Open and Endoscopic Approaches.
Review in Anesthesiology and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome: A Randomized Clinical Trial
Comparison of Ultrasound-guided Transverse Carpal Ligament Needle Release Via Different Approaches for Patients With Mild-to-moderate Carpal Tunnel Syndrome
Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- "Intraoperative pillar corticosteroid injection": does it improve clinical outcomes after carpal tunnel release surgery? A double-blind, randomized controlled study.BMC musculoskeletal disorders · 2025Trial
- Enhancing Recovery After Endoscopic Carpal Tunnel Release: The Role of Neurotrophic Supplementation.Plastic and reconstructive surgery. Global open · 2026Article
- Effectiveness of Endoscopic versus Open Carpal Tunnel Release on Severe Carpal Tunnel Syndrome.Journal of wrist surgery · 2026Article
- Early symptom aggravation following ulnar nerve transposition for cubital tunnel syndrome: incidence, predictive factors, and threshold-based risk stratification.Neurosurgical review · 2026Article
- Patient-reported outcomes and functional recovery after carpal tunnel surgery in a developing health care system: insights from clinical practice.Scientific reports · 2025Article
- Carpal Tunnel Syndrome: A Comprehensive Review.Cureus · 2025Review
- Safety and Efficacy of Carpal Tunnel Release Using a New Surgical Knife With and Without Ultrasound Guidance: Comparative Study in 100 Cadaveric Specimens.Journal of hand surgery global online · 2025Article
- Directly Visualized Carpal Tunnel Release via a Proximal Mini-Transverse Incision: Surgical Technique and Clinical Outcomes.Journal of clinical medicine · 2025Article
- The Role of Palmar Cutaneous Branch Release in Enhancing Surgical Outcomes for Severe Carpal Tunnel Syndrome.Journal of clinical medicine · 2025Article
- When Numbness and Tingling Play a Role-Sexual Function in Compressive Neuropathy.Journal of hand surgery global online · 2024Article
- Endoscopic Versus Open Carpal Tunnel Release: A Systematic Review of Outcomes and Complications.Cureus · 2024Review
- Carpal tunnel syndrome.Nature reviews. Disease primers · 2024Review
- Surgical Interventions for the Management of Carpal Tunnel Syndrome: A Narrative Review.Cureus · 2024Review
- Optimizing Recovery After Carpal Tunnel Syndrome Release Surgery: The Role of Counseling in Pain Management and Perioperative Functional Enhancement.Journal of multidisciplinary healthcare · 2024Article
- Open surgery for carpal tunnel syndrome: is it necessary to release the antebrachial fascia? A randomized clinical trial study.Frontiers in surgery · 2024Article
- Review
- Article
- Update on surgical procedures for carpal tunnel syndrome: What is the current evidence and practice? What are the future research directions?World journal of orthopedics · 2023Review
- Endoscopic carpal surgery in carpal tunnel syndrome: A systematic review.SAGE open medicine · 2023Review
- Research advances and trends in the surgical treatment of carpal tunnel syndrome from 2003 to 2022: A CiteSpace-based bibliometric analysis.Frontiers in neurology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 13 institutions in 3 countries.
Funding
Abstract
contextCarpal tunnel syndrome (CTS) is the most frequent peripheral compression-induced neuropathy observed in patients worldwide. Surgery is necessary when conservative treatments fail and severe symptoms persist. Traditional Open carpal tunnel release (OCTR) with visualization of carpal tunnel is considered the gold standard for decompression. However, Endoscopic carpal tunnel release (ECTR), a less invasive technique than OCTR is emerging as a standard of care in recent years. EVIDENCE ACQUISITION: Criteria for this systematic review were derived from Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Two review authors searched PubMed, MEDLINE, and the Cochrane Database in May 2018 using the following MeSH terms from 1993-2016: 'carpal tunnel syndrome,' 'median nerve neuropathy,' 'endoscopic carpal tunnel release,' 'endoscopic surgery,' 'open carpal tunnel release,' 'open surgery,' and 'carpal tunnel surgery.' Additional sources, including Google Scholar, were added. Also, based on bibliographies and consultation with experts, appropriate publications were identified. The primary outcome measure was pain relief.
resultsFor this analysis, 27 studies met inclusion criteria. Results indicate that ECTR produced superior post-operative pain outcomes during short-term follow-up. Of the studies meeting inclusion criteria for this analysis, 17 studies evaluated pain as a primary or secondary outcome, and 15 studies evaluated pain, pillar tenderness, or incision tenderness at short-term follow-up. Most studies employed a VAS for assessment, and the majority reported superior short-term pain outcomes following ECTR at intervals ranging from one hour up to 12 weeks. Several additional studies reported equivalent pain outcomes at short-term follow-up as early as one week. No study reported inferior short-term pain outcomes following ECTR.
conclusionsECTR and OCTR produce satisfactory results in pain relief, symptom resolution, patient satisfaction, time to return to work, and adverse events. There is a growing body of evidence favoring the endoscopic technique for pain relief, functional outcomes, and satisfaction, at least in the early post-operative period, even if this difference disappears over time. Several studies have demonstrated a quicker return to work and activities of daily living with the endoscopic technique.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.