Evidence map›Paper›PMID 34150584›Full record

ReviewAnesthesiology and pain medicine2020

Carpal Tunnel Release Surgery- A Systematic Review of Open and Endoscopic Approaches.

Vwaire Orhurhu, Sebastian Orman, Jacquelin Peck, Ivan Urits, Mariam Salisu Orhurhu, Mark R Jones, Laxmaiah Manchikanti, Alan D Kaye, Charles Odonkor, Sameer Hirji and 4 more

3 registry-linked trialsOpen access · diamondAbstract readReview
In one paragraph

Review in Anesthesiology and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05468814 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome: A Randomized Clinical Trial

TypeinterventionalSponsorHospital Universitario Reina Sofia de CordobaRan2022 to 2023Enrolled120ConditionsCarpal Tunnel SyndromeArmsZ-plasty, Conventional
NCT06251674 nacompletednot on this map

Comparison of Ultrasound-guided Transverse Carpal Ligament Needle Release Via Different Approaches for Patients With Mild-to-moderate Carpal Tunnel Syndrome

TypeinterventionalSponsorPeking University People's HospitalRan2020 to 2023Enrolled60ConditionsCarpal Tunnel SyndromeArmslong-axis needle release, short-axis needle release
NCT06902831 completednot on this mapstarted 2022, after this paper: background citation

Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome

TypeobservationalSponsorUniversity of BariRan2022 to 2024Enrolled497ConditionsCarpal Tunnel Syndrome (CTS)ArmsEndoscopic Carpal Tunnel Release, Open carpal tunnel release, Neurotrophic supplementation
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

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  12. Carpal tunnel syndrome.Nature reviews. Disease primers · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 3 countries.

Vwaire OrhurhuUniversity Of Pittsburgh Medical Center, Williamsport, PA, USA.
Sebastian OrmanDepartment of Orthopedics, Georgetown University School of Medicine, Washington, DC, USA.
Jacquelin PeckDepartment of Anesthesiology, Mt. Sinai Medical Center of Florida, Miami Beach, Florida, USA.
Ivan UritsDepartment of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA.ORCID https://orcid.org/0000-0002-3652-6085
Mariam Salisu OrhurhuDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Mark R JonesWeill Cornell Medicine, Weill Cornell Medicine Division of Pain Management, New York, NY, USA.
Laxmaiah ManchikantiPain Management Centers of America, Paducah, KY, USA.
Alan D KayeDepartment of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA.
Charles OdonkorDepartment of Anesthesia, Critical Care and Pain Medicine, Division of Pain, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Sameer HirjiDepartments of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Elyse M CornettDepartment of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA.
Farnad ImaniPain Research Center, Department of Anesthesiology and Pain Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0814-0772
Giustino VarrassiPaolo Procacci Foundation, Roma, Italy.ORCID https://orcid.org/0000-0002-3822-2923
Omar ViswanathDepartment of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA.ORCID https://orcid.org/0000-0002-6124-7037
Louisiana State University Health Sciences Center Shreveport · USBrigham and Women's Hospital · USCornell University · USCreighton University · USFondazione Roma · ITGeorgetown University · USHarvard University · USIran University of Medical Sciences · IRJohns Hopkins University · USMount Sinai Medical Center · USPain Management Centers Of America · USSouthCoast Health · USWilliams (United States) · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

contextCarpal tunnel syndrome (CTS) is the most frequent peripheral compression-induced neuropathy observed in patients worldwide. Surgery is necessary when conservative treatments fail and severe symptoms persist. Traditional Open carpal tunnel release (OCTR) with visualization of carpal tunnel is considered the gold standard for decompression. However, Endoscopic carpal tunnel release (ECTR), a less invasive technique than OCTR is emerging as a standard of care in recent years. EVIDENCE ACQUISITION: Criteria for this systematic review were derived from Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Two review authors searched PubMed, MEDLINE, and the Cochrane Database in May 2018 using the following MeSH terms from 1993-2016: 'carpal tunnel syndrome,' 'median nerve neuropathy,' 'endoscopic carpal tunnel release,' 'endoscopic surgery,' 'open carpal tunnel release,' 'open surgery,' and 'carpal tunnel surgery.' Additional sources, including Google Scholar, were added. Also, based on bibliographies and consultation with experts, appropriate publications were identified. The primary outcome measure was pain relief.

resultsFor this analysis, 27 studies met inclusion criteria. Results indicate that ECTR produced superior post-operative pain outcomes during short-term follow-up. Of the studies meeting inclusion criteria for this analysis, 17 studies evaluated pain as a primary or secondary outcome, and 15 studies evaluated pain, pillar tenderness, or incision tenderness at short-term follow-up. Most studies employed a VAS for assessment, and the majority reported superior short-term pain outcomes following ECTR at intervals ranging from one hour up to 12 weeks. Several additional studies reported equivalent pain outcomes at short-term follow-up as early as one week. No study reported inferior short-term pain outcomes following ECTR.

conclusionsECTR and OCTR produce satisfactory results in pain relief, symptom resolution, patient satisfaction, time to return to work, and adverse events. There is a growing body of evidence favoring the endoscopic technique for pain relief, functional outcomes, and satisfaction, at least in the early post-operative period, even if this difference disappears over time. Several studies have demonstrated a quicker return to work and activities of daily living with the endoscopic technique.

Indexed as

Carpal Tunnel SyndromeChronic PainDisabilityEndoscopic Carpal Tunnel ReleaseEndoscopic SurgeryEntrapment NeuropathyMedian NeuropathyOpen Carpal Tunnel Release

Identifiers

PMID34150584
PMCPMC8207842
OpenAlexW3117630271

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.