Evidence map›Paper›PMID 34150581›Full record

ReviewAnesthesiology and pain medicine2020

An Update on Treatment Modalities for Ulnar Nerve Entrapment: A Literature Review.

Neeraj Vij, Blake Traube, Roy Bisht, Ian Singleton, Elyse M Cornett, Alan D Kaye, Farnad Imani, Ali Mohammadian Erdi, Giustino Varrassi, Omar Viswanath and 1 more

Abstract readReview
In one paragraph

Review in Anesthesiology and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Occupational nerve injuries.Muscle & nerve · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Neeraj VijUniversity of Arizona College of Medicine - Phoenix, Phoenix, Arizona.ORCID https://orcid.org/0000-0002-7214-0411
Blake TraubeUniversity of Arizona College of Medicine - Phoenix, Phoenix, Arizona.
Roy BishtUniversity of Arizona College of Medicine - Phoenix, Phoenix, Arizona.
Ian SingletonUniversity of Arizona College of Medicine - Phoenix, Phoenix, Arizona.
Elyse M CornettLouisiana State University Health Shreveport, Department of Anesthesiology, Shreveport, Louisiana.
Alan D KayeLouisiana State University Health Shreveport, Department of Anesthesiology, Shreveport, Louisiana.
Farnad ImaniPain Research Center, Department of Anesthesiology and Pain Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0814-0772
Ali Mohammadian ErdiDepartment of Anesthesiology, Ardabil University of Medical Sciences, Ardabil, Iran.ORCID https://orcid.org/0000-0002-7005-4640
Giustino VarrassiPaolo ProcacciFoundation, Via Tacito 7, Roma, Italy.ORCID https://orcid.org/0000-0002-3822-2923
Omar ViswanathUniversity of Arizona College of Medicine - Phoenix, Phoenix, Arizona.ORCID https://orcid.org/0000-0002-6124-7037
Ivan UritsSouthcoast Health Physicians Group Pain Medicine, Wareham, Massachusetts.ORCID https://orcid.org/0000-0002-3652-6085

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextUlnar nerve entrapment is a relatively common entrapment syndrome second only in prevalence to carpal tunnel syndrome. The potential anatomic locations for entrapment include the brachial plexus, cubital tunnel, and Guyon's canal. Ulnar nerve entrapment is more so prevalent in pregnancy, diabetes, rheumatoid arthritis, and patients with occupations involving periods of prolonged elbow flexion and/or wrist dorsiflexion. Cyclists are particularly at risk of Guyon's canal neuropathy. Patients typically present with sensory deficits of the palmar aspect of the fourth and fifth digits, followed by motor symptoms, including decreased pinch strength and difficulty fastening shirt buttons or opening bottles. EVIDENCE ACQUISITION: Literature searches were performed using the below MeSH Terms using Mendeley version 1.19.4. Search fields were varied until further searches revealed no new articles. All articles were screened by title and abstract. Decision was made to include an article based on its relevance and the list of final articles was approved three of the authors. This included reading the entirety of the artice. Any question regarding the inclusion of an article was discussed by all authors until an agreement was reached.

resultsX-ray and CT play a role in diagnosis when a bony injury is thought to be related to the pathogenesis (i.e., fracture of the hook of the hamate.) MRI plays a role where soft tissue is thought to be related to the pathogenesis (i.e., tumor or swelling.) Electromyography and nerve conduction also play a role in diagnosis. Medical management, in conjunction with physical therapy, shows limited promise. However, minimally invasive techniques, including peripheral percutaneous electrode placement and ultrasound-guided electrode placement, have all been recently studied and show great promise. When these techniques fail, clinicians should resort to decompression, which can be done endoscopically or through an open incision. Endoscopic ulnar decompression shows great promise as a surgical option with minimal incisions.

conclusionsClinical diagnosis of ulnar nerve entrapment can often be delayed and requires the suspicion as well as a thorough neurological exam. Early recognition and diagnois are important for early institution of treatment. A wide array of diagnostic imaging can be useful in ruling out bony, soft tissue, or vascular etiologies, respectively. However, clinicians should resort to electrodiagnostic testing when a definitive diagnois is needed. Many new minimally invasive techniques are in the literature and show great promise; however, further large scale trials are needed to validate these techniques. Surgical options remains as a gold standard when adequate symptom relief is not achieved through minimally invasive means.

Indexed as

Guyon’s Canal NeuropathyMinimally InvasiveNon-Surgical Ulnar NerveSurgical Ulnar NerveUlnar CompressionUlnar Nerve Entrapment

Identifiers

PMID34150581
PMCPMC8207847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.