Evidence map›Paper›PMID 34150537›Full record

ArticleInternational journal of ophthalmology2021

Reliability of Chinese web-based ocular surface disease index questionnaire in dry eye patients: a randomized, crossover study.

Xin-Mei Zhang, Lan-Ting Yang, Qing Zhang, Qing-Xia Fan, Can Zhang, Yue You, Chen-Guang Zhang, Tie-Zhu Lin, Ling Xu, Salissou Moutari and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06269237 (Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment), which is not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06269237 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment

TypeinterventionalSponsorHe Eye HospitalRan2024 to 2024Enrolled30ConditionsDry EyeArmsM22, sham M22
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

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  15. Comparison of two treatments for dry eye disease after corneal refractive surgery.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Xin-Mei ZhangDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Lan-Ting YangDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Qing ZhangDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Qing-Xia FanDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Can ZhangDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Yue YouDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Chen-Guang ZhangDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Tie-Zhu LinDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Ling XuDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Salissou MoutariSchool of Mathematics and Physics, Queens University Belfast, University Road, Belfast, Northern Ireland BT7 1NN, United Kingdom.
Jonathan E MooreCathedral Eye Clinic, 89-91 Academy Street, Belfast, Northern Ireland BT1 2LS, United Kingdom.
Emmanuel E PazoDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
Wei HeDepartment of Ophthalmology, He Eye Specialists Hospital, Shenyang 110034, Liaoning Province, China.
He Eye Hospital · CNQueen's University Belfast · GBSecond Affiliated Hospital of Dalian Medical University · CNUniversity of Ulster · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the reliability of web-based version of ocular surface disease index in Chinese (C-OSDI) on clinically diagnosed dry eye disease (DE) patients.

methodsA total of 254 Chinese participants (51% male, 129/254; mean age: 27.90±9.06y) with DED completed paper- and web-based versions of C-OSDI questionnaires in a randomized crossover design. Ophthalmology examination and DED diagnosis were performed prior to the participants being invited to join the study. Participants were randomly designated to either group A (paper-based first and web-based second) or group B (web-based first and paper-based second). Final data analysis included participants that had successfully completed both versions of the C-OSDI. Demographic characteristics, test-retest reliability, and agreement of individual items, subscales, and total score were evaluated with intraclass correlation coefficients (ICC), Spearman rank correlation, Wilcoxon test and Rasch analysis.

resultsReliability indexes were adequate, Pearson correlation was greater than 0.8 and ICCs range was 0.827 to 0.982; total C-OSDI score was not statistically different between the two versions. The values of mean-squares fit statistics were very low compared to 1, indicating that the responses to the items by the model had a high degree of predictability. While comparing the favorability 72% (182/254) of the participants preferred web-based assessment.

conclusionWeb-based C-OSDI is reliable in assessing DED and correlation with the paper-based version is significant in all subscales and overall total score. Web-based C-OSDI can be administered to assess individuals with DED as participants predominantly favored online assessment.

Indexed as

dry eye diseaseocular surface disease indexRasch analysistest-retest reliabilityweb-based questionnaire

Identifiers

PMID34150537
PMCPMC8165610
OpenAlexW3164080628

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.