Evidence map›Paper›PMID 34150535›Full record

ArticleInternational journal of ophthalmology2021

Association of eleven single nucleotide polymorphisms with refractive disorders from Eskisehir, Turkey.

Nadir Unlu, Ebru Erzurumluoglu Gokalp, Serap Arslan, Oguz Cilingir, Muzaffer Bilgin, Engin Yildirim, Huseyin Gursoy

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nadir UnluDepartment of Ophthalmology, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Ebru Erzurumluoglu GokalpDepartment of Medical Genetics, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Serap ArslanDepartment of Medical Genetics, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Oguz CilingirDepartment of Medical Genetics, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Muzaffer BilginDepartment of Biostatistics, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Engin YildirimDepartment of Pharmacology, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Huseyin GursoyDepartment of Ophthalmology, Eskisehir Osmangazi University Medical Faculty, Eskisehir 26040, Turkey.
Eskişehir Osmangazi University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate relationship between refractive errors and eleven single nucleotide polymorphisms (SNPs) in

methodsA group of 212 participants with myopia (

resultsThe patients in this study consists of 47 female/44 male (age: 23.47±4.30) patients with myopia, 20 female/25 male (age: 31.20±8.02) with hyperopia and 33 female/43 male (age: 25.22±6.60) with emmetropia. The genotype distribution of the rs7618348 polymorphism, which was the only statistically significant one between myopia and emmetropia group. The genotype distribution of the rs3819545, rs3735520, rs7041, and rs2239182 polymorphisms, which were statistically significant between hyperopia and emmetropia groups.

conclusionThe importance of genetic predisposition to refractive errors with respect to etiology of the disease is revealed. It is known that polymorphism studies may differ because of genetic diversity among populations so larger cohort studies are required in different populations to enlighten the etiology of the refractive errors.

Indexed as

geneticshyperopiamyopiarefractive disorderssingle nucleotide polymorphismsTurkey

Identifiers

PMID34150535
PMCPMC8165615
OpenAlexW3165246729

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.