Evidence map›Paper›PMID 34150528›Full record

ArticleToxicology reports2021

The EU endocrine disruptors' regulation and the glyphosate controversy.

Paraskevi Kalofiri, Giorgos Balias, Fotios Tekos

Abstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Determination of glyphosate in breast milk of lactating women in a rural area from Paraná state, Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paraskevi KalofiriHarokopio University of Athens, Greece.
Giorgos BaliasHarokopio University of Athens, Greece.
Fotios TekosDepartment of Biochemistry-Biotechnology, University of Thessaly, Larissa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine disruptors are compounds that alter the functioning of the endocrine system of humans and wildlife. A large number of chemicals have been identified as EDs and humans can be exposed to them through dietary and/or environmental exposure (air, water, soil). At international level, scientific discussion on the topic of EDs focuses on the issue of setting out the scientific criteria according to which the key properties of these substances that render them EDs are determined. Regulatory action in EU has been impacted by the aforementioned discussion and, in particular, Regulation 2017/2100 and Regulation 2018/605 have been issued. However, these scientific criteria do not constitute a complete framework for the detection of EDs and, therefore, their adoption does not entail a fully effective human health protection. Moreover, glyphosate-based herbicides (GBH), are the most widely used pesticides worldwide. The glyphosate controversy turned the spotlight on pesticide regulation in the EU. The disagreement between IARC and regulatory evaluations of EFSA/ECHA has received great attention of citizens, organizations and stakeholders, as a result of methodological differences in the evaluation of the available evidence have been identified. This paper outlines the glyphosate controversy, following an overview of the EU EDs Regulation and pesticide legislation.

Indexed as

EDCEndocrine disruptorsEU regulationGlyphosatePesticide legislationPrecautionary principle

Identifiers

PMID34150528
PMCPMC8193069

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.