Evidence map›Paper›PMID 34150490›Full record

ArticleLeukemia research reports2021

A rare case of B cell lymphoblastic leukemia with inv(7)(p15q34) with review of literature.

Bernhisel Andrew, Orazi Attilio, Guar Sumit, Tonk Vijay, Ghafouri Sayed Reshad, Padilla Osvaldo

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bernhisel AndrewMedical student, Paul Foster School of Medicine, Texas Tech Health Sciences Center at El Paso, TX.
Orazi AttilioDepartment of Pathology, Texas Tech Health Sciences Center at El Paso, TX.
Guar SumitDepartment of Internal Medicine, Texas Tech Health Sciences Center at El Paso, TX.
Tonk VijayDepartment of Pediatrics, Texas Tech Health Sciences Center at Lubbock, TX.
Ghafouri Sayed ReshadDepartment of Internal Medicine, Texas Tech Health Sciences Center at El Paso, TX.
Padilla OsvaldoDepartment of Pathology, Texas Tech Health Sciences Center at El Paso, TX.
Texas Tech University Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inv(7)(p15q34) chromosomal abnormality which juxtaposes part of the HOXA gene cluster on 7p15 to the TCRβ locus on 7q34, has been described in a subset of cases of T-cell lymphoblastic leukemia, but its presence in cases of B-cell lymphoblastic leukemia is virtually unknown. Herewith, we report a case of a B-cell lymphoblastic leukemia with inv(7)(p15q34). The patient received standard induction chemotherapy, which failed to produce remission. After treatment with blinatumomab, a bispecific T-cell engager, the follow-up bone marrow biopsy showed no evidence of persistent/ relapsed B-cell lymphoblastic leukemia. The unique cytogenetics of this case may have contributed to its resistance of standard induction chemotherapy.

Identifiers

PMID34150490
PMCPMC8192865
OpenAlexW3170284807

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.