Evidence map›Paper›PMID 34150399›Full record

ArticleCureus2021

Sublingual Microcirculatory Characteristics of a Case of Profound Chemotherapy-Induced Anemia Treated With a Hemoglobin-Based Oxygen Carrier.

Jason Stankiewicz, Maniraj Jeyaraju, Sanjay Maheshwari, Andrew R Deitchman, Michael T McCurdy

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jason StankiewiczDivision of Pulmonary and Critical Care, University of Maryland School of Medicine, Baltimore, USA.
Maniraj JeyarajuDivision of Pulmonary and Critical Care, University of Maryland School of Medicine, Baltimore, USA.
Sanjay MaheshwariDivision of Pulmonary and Critical Care, University of Maryland School of Medicine, Baltimore, USA.
Andrew R DeitchmanCritical Care Medicine, Christiana Care Health System, Newark, USA.
Michael T McCurdyDivision of Pulmonary and Critical Care, University of Maryland School of Medicine, Baltimore, USA.
University of Maryland, Baltimore · USChristiana Care Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Handheld vital microscopy (HVM) can deepen our understanding of hematologic diseases and therapeutics. However, limited reports have assessed human microcirculation during profound anemia, and response to hemoglobin-based oxygen carriers (HBOCs). A 58-year-old woman presented with constitutional symptoms and was diagnosed with acute myeloblastic leukemia. Subsequently, the patient clinically decompensated and was found to have a hemoglobin of 1.9 g/dL. Human blood product administration was not consistent with her beliefs, and she received supportive care with HBOC-201. Concomitantly, her sublingual microcirculation revealed a markedly low microvascular flow index (2.59±0.26), proportion perfused vessels (66.8±18.8%), perfused vessel density (4.41±0.56 mm/mm

Indexed as

anemiahemoglobin-based oxygen carriermicrocirculationresuscitationsublingual

Identifiers

PMID34150399
PMCPMC8203304
OpenAlexW3161458461

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.