Evidence map›Paper›PMID 34150173›Full record

ArticleAmerican journal of translational research2021

The correlation study on homocysteine, blood lipids and blood glucose levels in patients with cerebral infarction.

Wen-Ling Li, Hua Sang, Xin Xu, Yuan-Yuan Zhang, Jie Gao, Bo-Hua Chen, Xiang-Ying Meng

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Molecular Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wen-Ling LiDepartment of Pharmacy, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Hua SangDepartment of Pharmacy, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Xin XuDepartment of Pharmacy, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Yuan-Yuan ZhangDepartment of Neurology, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Jie GaoDepartment of Pharmacy, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Bo-Hua ChenDepartment of Pharmacy, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Xiang-Ying MengDepartment of Pharmacy, Affiliated RICH Hospital of Nantong University Nantong 226010, Jiangsu, China.
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the correlation of changes in homocysteine (HCY) l, blood lipids and blood glucose levels in patients with cerebral infarction.

methods120 patients with cerebral infarction admitted to our hospital from February 2018 to February 2020 were selected as the experimental group, and 120 healthy volunteers in the same period were selected as the control group. The blood pressure and the homocysteine, blood lipids, blood glucose levels were compared; the experimental group was subdivided into single cerebral infarction group, combined diabetes group and combined hypertension group, and their blood lipid levels were compared with the control group; Spearman method was used to analyze the relationship between HCY, blood lipid, blood sugar levels and cerebral infarction.

results① The diastolic and systolic blood pressure levels of the experimental group were higher, whereas the control group were lower (P<0.05). ② The levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and TC/[high density lipoprotein cholesterol (HDL-C)] of the experimental group were higher, but the level of HDL-C was lower than that of the control group (all P<0.05). ③ The fasting blood glucose (FBG) and glycosylated hemoglobin (GHb) levels of the experimental group were higher than those of the control group (all P<0.05). ④ The HCY level in the experimental group was higher than that in the control group (P<0.05). ⑤ The levels of TC, TG, LDL-C and TC/HDL-C in single cerebral infarction group, combined diabetes group and combined hypertension group were higher, and HDL-C level was lower than that in control group (all P<0.05). ⑥ Spearman analysis revealed that HCY was positively correlated with TC, TG, LDL-C and FBG (all P<0.05).

conclusionThe level of HCY is positively correlated with the levels of TC, TG, LDL-C and FBG in patients with cerebral infarction.

Indexed as

blood lipidsblood sugarCerebral infarctioncorrelationhomocysteinelevel changes

Identifiers

PMID34150173
PMCPMC8205740
OpenAlexW3175379484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.