ArticleAmerican journal of translational research2021
Effect of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy on parotid gland function and quality of life in patients with nasopharyngeal carcinoma.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Longitudinal multi-b-value diffusion MRI for the early assessment of radiation-induced parotid injury in nasopharyngeal carcinoma.Frontiers in oncology · 2026Article
- Neck dose-limiting rings reduce head and neck lymphedema in early nasopharyngeal carcinoma patients undergoing IMRT: a dosimetric-clinical validation.Scientific reports · 2025Article
- Quality of life in disease-free survived patients with early-stage extranodal nasal-type NK/T-cell lymphoma after definitive intensity-modulated radiotherapy: a cross-sectional study of 310 cases.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Predictive value of delta radiomics in xerostomia after chemoradiotherapy in patients with stage III-IV nasopharyngeal carcinoma.Radiation oncology (London, England) · 2024Article
- Analysis of the risk factors of the radiation-induced encephalopathy in nasopharyngeal carcinoma: A retrospective cohort study.Open medicine (Warsaw, Poland) · 2024Article
- Research Value of Intensity Modulated Radiation Therapy in Alleviating Parotid Gland Function Injury in Patients with Stage N0 Nasopharyngeal Carcinoma from Physical and Dosimetric Aspects.Computational and mathematical methods in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effects of three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) on parotid gland function and quality of life in patients with nasopharyngeal carcinoma (NPC).
methodsNinety-six patients with NPC diagnosed and treated in our hospital were divided into two groups using a random number table. The control group was treated with three-dimensional conformal radiotherapy and the research group was treated with intensity-modulated radiotherapy. Observation and comparison were conducted for differences of baseline indicators between the two groups including; short-term response rate, relevant indicators regarding parotid gland function before and after treatment, uptake index (UI) and excretion index (EI), dry mouth (xerostomia) grading and quality of life indicators after treatment, and the prognosis of patients.
resultsThere was no significant difference in baseline data between the two groups (all P>0.05). The short-term response rate in the research group was significantly higher than that in the control group (P<0.05). After treatment, UI and EI in both groups were significantly decreased compared to those before treatment (all P<0.05); UI and EI in the research group were significantly higher than those in control group (all P<0.05). Dry mouth grading in the research group was significantly lower than that in the control group (all P<0.05). After treatment, the levels of related indicators regarding quality of life, local recurrence-free rate, and distant metastasis-free rate in the research group were higher than those in the control group (all P<0.05).
conclusionIMRT for patients with NPC can significantly improve short-term response rate, reduce mouth dryness and parotid gland injury after radiotherapy, enhance quality of life, and facilitate the prognosis of patients.
Indexed as
Identifiers
34150118PMC8205664W3174832280What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.