Evidence map›Paper›PMID 34150090›Full record

ArticleAmerican journal of translational research2021

Sodium bicarbonated Ringer's solution effectively improves coagulation function and lactic acid metabolism in patients with severe multiple injuries and traumatic shock.

Jianzhong Ma, Shengjin Han, Xiaolin Liu, Zhengwu Zhou

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jianzhong MaDepartment of Emergency Surgery, Lu'an Hospital Affiliated to Anhui Medical University Lu'an, Anhui Province, China.
Shengjin HanDepartment of Emergency Surgery, Lu'an Hospital Affiliated to Anhui Medical University Lu'an, Anhui Province, China.
Xiaolin LiuDepartment of Emergency Surgery, Lu'an Hospital Affiliated to Anhui Medical University Lu'an, Anhui Province, China.
Zhengwu ZhouDepartment of Emergency Surgery, Lu'an Hospital Affiliated to Anhui Medical University Lu'an, Anhui Province, China.
West Anhui University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effect of sodium bicarbonated Ringer's solution on the coagulation function and the lactic acid metabolism in patients with severe multiple injuries and traumatic shock.

methodsA prospective, randomized controlled study was designed to enroll 50 patients with severe multiple injuries and traumatic shock. The enrolled patients were randomly assigned into a Test group (n=25) or a Control group (n=25), which received restrictive fluid resuscitation with sodium bicarbonated Ringer's solution or sodium lactated Ringer's solution, respectively. The success rate of rescue, the changes in coagulation function indices, lactic acid level, arterial blood pH level, hemorheological indices, blood pressure and heart rate before and after resuscitation, as well as the shock-related complications were observed.

resultsThe coagulation function of the Test group was significantly improved after resuscitation as compared with the Control group (P<0.05). After resuscitation, the Test group had significantly lower lactic acid level and significantly higher pH level than those of the Control group (both P<0.05). The hemorheological indices of the Test group were improved more significantly after resuscitation as compared with those of the Control group (P<0.05). There was no significant difference in the success rate of rescue between the Test group and the Control group (92.0% vs. 80.0%; P>0.05), but the total incidence of complications in the Test group was significantly lower than that in the Control group (16.0% vs. 56.0%; P<0.01).

conclusionSodium bicarbonated Ringer's solution is effective in early resuscitation for patients with severe multiple injuries and traumatic shock through improving the coagulation function and lactic acid metabolism, reducing the risk of related complications and improving the clinical outcome in patients.

Indexed as

coagulation functionlactic acidmultiple injuries with traumatic shockSodium bicarbonated Ringer’s solution

Identifiers

PMID34150090
PMCPMC8205763
OpenAlexW3173956253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.