Evidence map›Paper›PMID 34150020›Full record

ArticleAmerican journal of translational research2021

METTL3 induces bone marrow mesenchymal stem cells osteogenic differentiation and migration through facilitating M1 macrophage differentiation.

Hong Lei, Mingyu He, Xiaoqi He, Guanghui Li, Yang Wang, Yuelin Gao, Gege Yan, Quan Wang, Tao Li, Guoxin Liu and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. METTL3: a multifunctional regulator in diseases.Molecular and cellular biochemistry · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. The role of mGenes & diseases · 2024
    Review
  11. Review
  12. Exploring the impact of mFrontiers in immunology · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. METTL3-mCell proliferation · 2022
    Article
  17. METTL3 stabilizes HDAC5 mRNA in an mCell death discovery · 2022
    Article
  18. Article
  19. Emerging role of m6A modification in osteogenesis of stem cells.Journal of bone and mineral metabolism · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hong LeiDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Mingyu HeDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Xiaoqi HeDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Guanghui LiDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Yang WangDepartment of Pharmacy, The Second Affiliated Hospital of Harbin Medical University Harbin 150081, China.
Yuelin GaoDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Gege YanDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Quan WangDepartment of Clinical Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Tao LiDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Guoxin LiuDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Weijie DuDepartment of Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China.
Ye YuanDepartment of Pharmacy, The Second Affiliated Hospital of Harbin Medical University Harbin 150081, China.
Lei YangDepartment of Orthopedics, The First Affiliated Hospital of Harbin Medical University Harbin 150081, China.
Harbin Medical University · CNSecond Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the crucial role of m

Indexed as

BMSCsmacrophageMETTL3migrationosteogenic differentiation

Identifiers

PMID34150020
PMCPMC8205672
OpenAlexW3175140391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.