Evidence map›Paper›PMID 34149953›Full record

ArticleArchaeological and anthropological sciences2021

The elusive parasite: comparing macroscopic, immunological, and genomic approaches to identifying malaria in human skeletal remains from Sayala, Egypt (third to sixth centuries AD).

Alvie Loufouma Mbouaka, Michelle Gamble, Christina Wurst, Heidi Yoko Jäger, Frank Maixner, Albert Zink, Harald Noedl, Michaela Binder

Open access · hybridAbstract read
In one paragraph

Article in Archaeological and anthropological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Revealing tattoo traditions in ancient Nubia through multispectral imaging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Pathogen prospecting of museums: Reconstructing malaria epidemiology.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Alvie Loufouma MbouakaInstitute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, 1090 Vienna, Austria.ORCID 0000-0003-4561-8026
Michelle GambleBioarchaeology Department, Austrian Archaeological Institute at the Austrian Academy of Sciences, Franz Klein-Gasse 1, 1190 Vienna, Austria.ORCID 0000-0001-6282-4206
Christina WurstInstitute for Mummy Studies, EURAC Research, Viale Druso 1, 39100 Bolzano, Italy.ORCID 0000-0001-5214-2615
Heidi Yoko JägerInstitute for Mummy Studies, EURAC Research, Viale Druso 1, 39100 Bolzano, Italy.ORCID 0000-0001-6946-9112
Frank MaixnerInstitute for Mummy Studies, EURAC Research, Viale Druso 1, 39100 Bolzano, Italy.ORCID 0000-0003-2846-8994
Albert ZinkInstitute for Mummy Studies, EURAC Research, Viale Druso 1, 39100 Bolzano, Italy.ORCID 0000-0002-1461-747X
Harald NoedlInstitute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, 1090 Vienna, Austria.
Michaela BinderBioarchaeology Department, Austrian Archaeological Institute at the Austrian Academy of Sciences, Franz Klein-Gasse 1, 1190 Vienna, Austria.ORCID 0000-0002-3105-5878
Eurac Research · ITAustrian Academy of Sciences · ATEnglish Heritage · GBMedical University of Vienna · ATU.S. President's Malaria Initiative · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although malaria is one of the oldest and most widely distributed diseases affecting humans, identifying and characterizing its presence in ancient human remains continue to challenge researchers. We attempted to establish a reliable approach to detecting malaria in human skeletons using multiple avenues of analysis: macroscopic observations, rapid diagnostic tests, and shotgun-capture sequencing techniques, to identify pathological changes, SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12520-021-01350-z.

Indexed as

aDNAImmunoassaysMalariaPalaeopathologyShotgun-capture sequencing

Identifiers

PMID34149953
PMCPMC8202054
OpenAlexW3166969606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.