Evidence map›Paper›PMID 34149910›Full record

ArticleJournal of Cancer2021

MST4 negatively regulates the EMT, invasion and metastasis of HCC cells by inactivating PI3K/AKT/Snail1 axis.

Mei-Juan Dian, Jing Li, Xiao-Ling Zhang, Zi-Jian Li, Ying Zhou, Wei Zhou, Qiu-Ling Zhong, Wen-Qian Pang, Xiao-Lin Lin, Tao Liu and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Journal of gastrointestinal oncology · 2026
    Article
  2. Article
  3. Article
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  5. Frontiers in cell and developmental biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Mei-Juan DianCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Jing LiRadiotherapy Center, the First People's Hospital of Chenzhou, Xiangnan University, Chenzhou 423000, China.
Xiao-Ling ZhangDepartment of Physiology, Faculty of Basic Medical Sciences, Guilin Medical University, Guilin 541004, China.
Zi-Jian LiCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Ying ZhouCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Wei ZhouCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Qiu-Ling ZhongState Key Laboratory of Organ Failure Research, Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong Province Key Laboratory of Psychiatric Disorders, Collaborative Innovation Center for Brain Science, Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Wen-Qian PangCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Xiao-Lin LinCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Tao LiuCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yi-An LiuCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yong-Long LiInstitute of Comparative Medicine & Laboratory Animal Center, Southern Medical University, Guangzhou 510515, China.
Liu-Xin HanThe third people's hospital of Kunming (The Sixth Affiliated Hospital of Dali University), Kunming 650041, China.
Wen-Tao ZhaoDepartment of Gastrointestinal Oncology, The Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital, Yunnan Cancer Center), Kunming 650118, China.
Jun-Shuang JiaCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Sheng-Jun XiaoDepartment of Pathology, the Second Affiliated Hospital, Guilin Medical University, Guilin 541199, China.
Dong XiaoCancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Jia-Wei XiaThe third people's hospital of Kunming (The Sixth Affiliated Hospital of Dali University), Kunming 650041, China.
Wei-Chao HaoDepartment of Oncology, The First Affiliation Hospital of Guangdong Pharmaceutical University, Guangzhou 510062, China.
Southern Medical University · CNGuilin Medical University · CNChenzhou First People's Hospital · CNFirst Affiliated Hospital of Guangdong Pharmaceutical University · CNKunming Medical University · CNMinistry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EMTHepatocellular carcinomaMetastasisMST4PI3K/AKTPrognosisSnail1

Identifiers

PMID34149910
PMCPMC8210547
OpenAlexW3173117420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.