Evidence map›Paper›PMID 34149691›Full record

Observational studyFrontiers in immunology2021

Association of Polymorphisms in T-Cell Activation Costimulatory/Inhibitory Signal Genes With Allograft Kidney Rejection Risk.

Jose Luis Santiago, Luis Sánchez-Pérez, Isabel Pérez-Flores, Maria Angeles Moreno de la Higuera, Natividad Calvo Romero, Javier Querol-García, Elena Urcelay, Ana Isabel Sánchez-Fructuoso

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Liver cirrhosis and immune dysfunction.International immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jose Luis SantiagoLab. Genetics and Molecular Basis of Complex Diseases, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Luis Sánchez-PérezLab. Genetics and Molecular Basis of Complex Diseases, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Isabel Pérez-FloresNephrology Department Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, IdISSC, Madrid, Spain.
Maria Angeles Moreno de la HigueraNephrology Department Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, IdISSC, Madrid, Spain.
Natividad Calvo RomeroNephrology Department Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, IdISSC, Madrid, Spain.
Javier Querol-GarcíaLab. Genetics and Molecular Basis of Complex Diseases, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Elena UrcelayLab. Genetics and Molecular Basis of Complex Diseases, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Ana Isabel Sánchez-FructuosoNephrology Department Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, IdISSC, Madrid, Spain.
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESHospital Clínico San Carlos · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genes

Indexed as

Polymorphism, Single NucleotideAllelesAllograftsB7-2 AntigenCD28 AntigensCTLA-4 AntigenGene FrequencyGenotypeGraft RejectionHumansKidney TransplantationLinkage DisequilibriumLymphocyte ActivationMultivariate AnalysisRetrospective StudiesRisk FactorsB7-2 AntigenCD28 AntigensCTLA-4 AntigenCTLA4 protein, humanallograft rejectionBanff classificationcytotoxic T-lymphocyte associated protein 4kidney transplantationpolymorphism

Identifiers

PMID34149691
PMCPMC8206554
OpenAlexW3169278056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.