Evidence map›Paper›PMID 34149677›Full record

ArticleFrontiers in microbiology2021

A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase.

Zhihao Wang, Hongliang Wang, Nancy Mulvenna, Maximo Sanz-Hernandez, Peipei Zhang, Yanqing Li, Jia Ma, Yawen Wang, Steve Matthews, Sivaramesh Wigneshweraraj and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. A methylome-derived mbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in theProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Article
  10. Bacteriophages of Thermophilic 'Microorganisms · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Zhihao WangBioBank, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Hongliang WangDepartment of Pathogen Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Nancy MulvennaMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Maximo Sanz-HernandezMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Peipei ZhangBioBank, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yanqing LiBioBank, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jia MaBioBank, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yawen WangBioBank, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Steve MatthewsMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Sivaramesh WigneshwerarajMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Bing LiuBioBank, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Imperial College London · GBFirst Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA mimicry by proteins is a strategy that employed by some proteins to occupy the binding sites of the DNA-binding proteins and deny further access to these sites by DNA. Such proteins have been found in bacteriophage, eukaryotic virus, prokaryotic, and eukaryotic cells to imitate non-coding functions of DNA. Here, we report another phage protein Gp44 from bacteriophage SPO1 of

Indexed as

bacteriophageDNA binding abilityDNA mimic proteinintrinsic disordered proteinRNA polymerase

Identifiers

PMID34149677
PMCPMC8208478
OpenAlexW3170342737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.