Evidence map›Paper›PMID 34149676›Full record

ReviewFrontiers in microbiology2021

Programmed Deviations of Ribosomes From Standard Decoding in Archaea.

Federica De Lise, Andrea Strazzulli, Roberta Iacono, Nicola Curci, Mauro Di Fenza, Luisa Maurelli, Marco Moracci, Beatrice Cobucci-Ponzano

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Federica De LiseInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
Andrea StrazzulliDepartment of Biology, University of Naples Federico II, Complesso Universitario di Monte S. Angelo, Naples, Italy.
Roberta IaconoInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
Nicola CurciInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
Mauro Di FenzaInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
Luisa MaurelliInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
Marco MoracciInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
Beatrice Cobucci-PonzanoInstitute of Biosciences and BioResources - National Research Council of Italy, Naples, Italy.
National Research Council · ITUniversity of Naples Federico II · ITInstitute of Biosciences and Bioresources · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic code decoding, initially considered to be universal and immutable, is now known to be flexible. In fact, in specific genes, ribosomes deviate from the standard translational rules in a programmed way, a phenomenon globally termed recoding. Translational recoding, which has been found in all domains of life, includes a group of events occurring during gene translation, namely stop codon readthrough, programmed ± 1 frameshifting, and ribosome bypassing. These events regulate protein expression at translational level and their mechanisms are well known and characterized in viruses, bacteria and eukaryotes. In this review we summarize the current state-of-the-art of recoding in the third domain of life. In Archaea, it was demonstrated and extensively studied that translational recoding regulates the decoding of the 21st and the 22nd amino acids selenocysteine and pyrrolysine, respectively, and only one case of programmed -1 frameshifting has been reported so far in

Indexed as

alpha-fucosidasearchaeaframeshiftingpyrrolysinerecodingselenocysteine

Identifiers

PMID34149676
PMCPMC8211752
OpenAlexW3167642373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.