Evidence map›Paper›PMID 34149614›Full record

ArticleFrontiers in endocrinology2021

Serum Anti-Müllerian Hormone Levels Were Negatively Associated With Body Fat Percentage in PCOS Patients.

Er Luo, Jinxiao Zhang, Jiahui Song, Di Feng, Yaxin Meng, Hongyu Jiang, Da Li, Yuanyuan Fang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Study of association between serum anti-Müllerian hormone, glucose intolerance, and metabolic syndrome in women with polycystic ovarian syndrome: A comparative study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Er LuoCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Jinxiao ZhangCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Jiahui SongCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Di FengCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Yaxin MengCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Hongyu JiangCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Da LiCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Yuanyuan FangCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity is a state of excess body fat accumulation, and appears to be closely associated with polycystic ovary syndrome (PCOS). Notably, plausible biological pathways through which obesity can regulate anti-Müllerian hormone (AMH) production have been proposed, and women with PCOS characteristically have an increased AMH level. Body fat accumulation can be described by body fat percentage (BFP). However, the relationship between BFP and AMH still remains unclear. Materials and Methods: A total of 87 controls and 156 PCOS patients were divided into lean and overweight/obese groups, and the PCOS patients were further divided into hyper-AMH and normal-AMH subgroups. Univariate regression was used to assess the unadjusted relationship between AMH and outcome variables, multivariable regression analysis was performed to test whether and how serum AMH levels were associated with BFP after adjusting for other co-variables. Receiver-operating characteristic (ROC) curve analyses were used to test the utility of BFP for the diagnosis of PCOS. Results: BFP was higher in PCOS patients compared with controls, regardless of obesity. Serum AMH levels were negatively associated with BFP in the PCOS group (r = -0.371; Conclusions: Herein, we described the negative correlation between BFP and serum AMH levels for the first time, and the present results highlight the importance of further investigation into the role of BFP, especially in body fat-related AMH change as it relates to the underlying pathogenesis of PCOS.

Indexed as

Adipose TissueAdultAnti-Mullerian HormoneBody Fat DistributionChinaFemaleHumansPolycystic Ovary SyndromeROC CurveYoung AdultAnti-Mullerian Hormoneanti-Müllerian hormonebody fat percentageobesitypolycystic ovary syndrome (PCOS)serum

Identifiers

PMID34149614
PMCPMC8213015
OpenAlexW3173001835

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.