Evidence map›Paper›PMID 34149609›Full record

ArticleFrontiers in endocrinology2021

Isolating the Role of Corticosterone in the Hypothalamic-Pituitary-Gonadal Transcriptomic Stress Response.

Suzanne H Austin, Rayna M Harris, April M Booth, Andrew S Lang, Victoria S Farrar, Jesse S Krause, Tyler A Hallman, Matthew MacManes, Rebecca M Calisi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Suzanne H AustinDepartment of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA, United States.
Rayna M HarrisDepartment of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA, United States.
April M BoothDepartment of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA, United States.
Andrew S LangDepartment of Molecular, Cellular and Biomedical Sciences, The University of New Hampshire, Durham, NH, United States.
Victoria S FarrarDepartment of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA, United States.
Jesse S KrauseDepartment of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA, United States.
Tyler A HallmanDepartment of Fisheries and Wildlife, Oregon State University, Corvallis, OR, United States.
Matthew MacManesDepartment of Molecular, Cellular and Biomedical Sciences, The University of New Hampshire, Durham, NH, United States.
Rebecca M CalisiDepartment of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA, United States.
University of California, Davis · USUniversity of New Hampshire · USOregon State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigation of the negative impacts of stress on reproduction has largely centered around the effects of the adrenal steroid hormone, corticosterone (CORT), and its influence on a system of tissues vital for reproduction-the hypothalamus of the brain, the pituitary gland, and the gonads (the HPG axis). Research on the action of CORT on the HPG axis has predominated the stress and reproductive biology literature, potentially overshadowing other influential mediators. To gain a more complete understanding of how elevated CORT affects transcriptomic activity of the HPG axis, we experimentally examined its role in male and female rock doves (

Indexed as

AnimalsColumbidaeCorticosteroneFemaleGene Expression ProfilingGonadsHypothalamo-Hypophyseal SystemHypothalamusMalePituitary GlandReproductionSex FactorsStress, PhysiologicalTranscriptomeCorticosteroneacute stressbirds (Aves)corticosteronehypothalamic-pituitary-gonad axistranscriptomics

Identifiers

PMID34149609
PMCPMC8207517
OpenAlexW3169462143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.