Evidence map›Paper›PMID 34149428›Full record

ArticleFrontiers in pharmacology2021

Three-Dimensional Culture of Ameloblast-Originated HAT-7 Cells for Functional Modeling of Defective Tooth Enamel Formation.

Anna Földes, Thanyaporn Sang-Ngoen, Kristóf Kádár, Róbert Rácz, Ákos Zsembery, Pamela DenBesten, Martin C Steward, Gábor Varga

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Roles of calcium in ameloblasts during tooth development: A scoping review.Journal of Taibah University Medical Sciences · 2025
    Review
  4. Review
  5. Ameloblastin promotes polarization of ameloblast cell lines in a 3-D cell culture system.Matrix biology : journal of the International Society for Matrix Biology · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Anna FöldesDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Thanyaporn Sang-NgoenDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Kristóf KádárDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Róbert RáczDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Ákos ZsemberyDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Pamela DenBestenDepartment of Orofacial Sciences, University of California San Francisco, San Francisco, CA, United States.
Martin C StewardDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Gábor VargaDepartment of Oral Biology, Semmelweis University, Budapest, Hungary.
Semmelweis University · HUUniversity of California, San Francisco · US

Funding

Enamel biomineralization; the role of pH cyclingR01DE027971 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Pamela K Den Besten · 2019 to 2026
$4.5M
NIDCR NIH HHS R01 DE027971
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ameloblastamelogenesisbicarbonate transportcalcium signalingfluorideHAT-7intracellular pHtight junction

Identifiers

PMID34149428
PMCPMC8206558
OpenAlexW3166451766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.