Evidence map›Paper›PMID 34149425›Full record

ArticleFrontiers in pharmacology2021

Bio-Guided Fractionation and Molecular Networking Reveal Fatty Acids to Be Principal Anti-Parasitic Compounds in Nordic Seaweeds.

Charlotte Smith Bonde, Louis Bornancin, Yi Lu, Henrik Toft Simonsen, María Martínez-Valladares, Miguel Peña-Espinoza, Helena Mejer, Andrew R Williams, Stig Milan Thamsborg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Evaluation of the Anti-Antibiotics (Basel, Switzerland) · 2023
    Article
  8. The Brown AlgaPathogens (Basel, Switzerland) · 2023
    Article
  9. Development of In Vitro Assays with the Canine HookwormPathogens (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Antimicrobial, Antivirulence, and Antiparasitic Potential ofAntibiotics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Charlotte Smith BondeDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.
Louis BornancinDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Yi LuDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Henrik Toft SimonsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
María Martínez-ValladaresInstituto de Ganadería de Montaña (CSIC-Universidad de León), Department of Animal Health, León, Spain.
Miguel Peña-EspinozaInstituto de Farmacologia y Morfofisiologia, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile.
Helena MejerDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.
Andrew R WilliamsDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.
Stig Milan ThamsborgDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.
University of Copenhagen · DKTechnical University of Denmark · DKAustral University of Chile · CLInstituto de Ganadería de Montaña · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Widespread use of antimicrobial drugs has led to high levels of drug-resistance in pathogen populations and a need for novel sources of anti-bacterial and anti-parasitic compounds. Macroalgae (seaweed) are potentially a rich source of bioactive compounds, and several species have traditionally been used as vermifuges. Here, we investigated the anti-parasitic properties of four common cold-water Nordic seaweeds;

Indexed as

alpha-linolenic acidanthelminthiceicosapentaenoic acidfatty acidsmacroalgaestearidonic acid

Identifiers

PMID34149425
PMCPMC8206555
OpenAlexW3171785306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.