Evidence map›Paper›PMID 34149391›Full record

ArticleFrontiers in aging neuroscience2021

Disrupted Network Topology Contributed to Spatial Navigation Impairment in Patients With Mild Cognitive Impairment.

Weiping Li, Hui Zhao, Zhao Qing, Zuzana Nedelska, Sichu Wu, Jiaming Lu, Wenbo Wu, Zhenyu Yin, Jakub Hort, Yun Xu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Weiping LiDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Hui ZhaoDepartment of Neurology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Zhao QingDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Zuzana NedelskaDepartment of Neurology, The Czech Brain Ageing Study, Memory Clinic, Second Faculty of Medicine-Charles University, University Hospital in Motol, Prague, Czechia.
Sichu WuDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Jiaming LuDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Wenbo WuDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Zhenyu YinDepartment of Geriatrics, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Jakub HortDepartment of Neurology, The Czech Brain Ageing Study, Memory Clinic, Second Faculty of Medicine-Charles University, University Hospital in Motol, Prague, Czechia.
Yun XuDepartment of Neurology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Bing ZhangDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Nanjing Drum Tower Hospital · CNInternational Clinical Research Center, St. Anne's University Hospital Brno · CZUniversity Hospital in Motol · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impairment in spatial navigation (SN) and structural network topology is not limited to patients with Alzheimer's disease (AD) dementia and can be detected earlier in patients with mild cognitive impairment (MCI). We recruited 32 MCI patients (65.91 ± 11.33 years old) and 28 normal cognition patients (NC; 69.68 ± 10.79 years old), all of whom underwent a computer-based battery of SN tests evaluating egocentric, allocentric, and mixed SN strategies and diffusion-weighted and T

Indexed as

clustering coefficientgraph theorymild cognitive impairmentnetwork topologyspatial navigation

Identifiers

PMID34149391
PMCPMC8210585
OpenAlexW3168579366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.