ReviewCurrent opinion in colloid & interface science2021
Surfactants - Compounds for inactivation of SARS-CoV-2 and other enveloped viruses.
Review in Current opinion in colloid & interface science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 78 citations in OpenAlex.
- Intrinsic Fluorescence as a Probe of Structural Dynamics and Interactions of Human Adenovirus with Surfactants and Liposomes.Journal of fluorescence · 2026Article
- Enhanced virucidal activity of quaternary ammonium compound-thymol combinations: influence of mucin and mucoadhesive polymers.Archives of virology · 2026Article
- Environmental and microbial factors shaping SARS-CoV-2 RNA decay in wastewater: insights from batch tests and a lab-scale sewer pipeline simulator.Scientific reports · 2026Article
- Differential mechanisms of SARS-CoV-2 inactivation by anionic surfactants: a comparative study of fatty acid salts and synthetic surfactants.Scientific reports · 2026Article
- Efficacy of Antimicrobials Against Enveloped and Non-Enveloped Viruses on Porous Materials: A Review.Microorganisms · 2025Review
- Relationship between Antiviral Activity against Influenza A Virus Induced by Compound Combinations and Changes in the Physical Properties of Lipid Bilayers.ACS pharmacology & translational science · 2025Article
- Membrane-Targeting Antivirals.International journal of molecular sciences · 2025Review
- Article
- Influence of cell culture-derived media and environmental contaminants on the effect of feline calicivirus inactivation agents.Scientific reports · 2025Article
- Article
- SARS-CoV-2 FP1 Destabilizes Lipid Membranes and Facilitates Pore Formation.International journal of molecular sciences · 2025Article
- Ionic surfactants alter virus surface properties and electrostatic interactions in aqueous systems.FEMS microbes · 2025Article
- Non-enveloped virus inactivation potency of sodium dodecyl sulfate with citric and glutamic acids.Frontiers in microbiology · 2025Article
- Mechanisms of action of microbicides commonly used in infection prevention and control.Microbiology and molecular biology reviews : MMBR · 2024Review
- Stabilization of an Infectious Enveloped Virus by Spray-Drying and Lyophilization.Journal of pharmaceutical sciences · 2024Article
- Broad-Spectrum Supramolecularly Reloadable Antimicrobial Coatings.ACS applied materials & interfaces · 2024Article
- Prebiotic inulin ameliorates SARS-CoV-2 infection in hamsters by modulating the gut microbiome.NPJ science of food · 2024Article
- Effect of mechanical stresses on viral capsid disruption during droplet formation and drying.Colloids and surfaces. B, Biointerfaces · 2024Article
- Interplay of TLR4 and SARS-CoV-2: Unveiling the Complex Mechanisms of Inflammation and Severity in COVID-19 Infections.Journal of inflammation research · 2024Review
- Effectiveness of TRIzol in Inactivating Animal Pathogens.Applied biosafety : journal of the American Biological Safety Association · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We provide here a general view on the interactions of surfactants with viruses, with a particular emphasis on how such interactions can be controlled and employed for inhibiting the infectivity of enveloped viruses, including coronaviruses. The aim is to provide to interested scientists from different fields, including chemistry, physics, biochemistry, and medicine, an overview of the basic properties of surfactants and (corona)viruses, which are relevant to understanding the interactions between the two. Various types of interactions between surfactant and virus are important, and they act on different components of a virus such as the lipid envelope, membrane (envelope) proteins and nucleocapsid proteins. Accordingly, this cannot be a detailed account of all relevant aspects but instead a summary that bridges between the different disciplines. We describe concepts and cover a selection of the relevant literature as an incentive for diving deeper into the relevant material. Our focus is on more recent developments around the COVID-19 pandemic caused by SARS-CoV-2, applications of surfactants against the virus, and on the potential future use of surfactants for pandemic relief. We also cover the most important aspects of the historical development of using surfactants in combatting virus infections. We conclude that surfactants are already playing very important roles in various directions of defence against viruses, either directly, as in disinfection, or as carrier components of drug delivery systems for prophylaxis or treatment. By designing tailor-made surfactants, and consequently, advanced formulations, one can expect more and more effective use of surfactants, either directly as antiviral compounds or as part of more complex formulations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.