Evidence map›Paper›PMID 34149191›Full record

ArticleNeural computing & applications2021

Performance of machine learning classification models of autism using resting-state fMRI is contingent on sample heterogeneity.

Maya A Reiter, Afrooz Jahedi, A R Jac Fredo, Inna Fishman, Barbara Bailey, Ralph-Axel Müller

Abstract read
In one paragraph

Article in Neural computing & applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
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  4. Unsupervised Dimensionality Reduction Techniques for the Assessment of ASD Biomarkers.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2025
    Article
  5. Article
  6. Article
  7. Identification of Autism Spectrum Disorder Using Topological Data Analysis.Journal of imaging informatics in medicine · 2024
    Article
  8. Article
  9. Article
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  11. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maya A ReiterBrain Development Imaging Lab (BDIL), Psychology, San Diego State University (SDSU), 6363 Alvarado Ct. Suite 200, San Diego, CA 92120, USA.
Afrooz JahediComputational Science, San Diego State University/ Claremont Graduate University's Joint Doctoral Program, San Diego, CA, USA.
A R Jac FredoComputational Science, San Diego State University/ Claremont Graduate University's Joint Doctoral Program, San Diego, CA, USA.
Inna FishmanBrain Development Imaging Lab (BDIL), Psychology, San Diego State University (SDSU), 6363 Alvarado Ct. Suite 200, San Diego, CA 92120, USA.
Barbara BaileyDepartment of Mathematics and Statistics, San Diego State University, San Diego, California.
Ralph-Axel MüllerBrain Development Imaging Lab (BDIL), Psychology, San Diego State University (SDSU), 6363 Alvarado Ct. Suite 200, San Diego, CA 92120, USA.

Funding

Integrity and Dynamic Processing Efficiency of Networks in ASDR01MH101173 · NIMH · SAN DIEGO STATE UNIVERSITY · PI MUELLER, RALPH-AXEL · 2014 to 2018
$3.2M
Linking Local Activity and Functional Connectivity in AutismR01MH081023 · NIMH · SAN DIEGO STATE UNIVERSITY · PI MUELLER, RALPH-AXEL · 2009 to 2013
$1.9M
Multimodal Imaging of Social Brain Networks in ASDK01MH097972 · NIMH · SAN DIEGO STATE UNIVERSITY · PI FISHMAN, INNA · 2012 to 2015
$599k
NIMH NIH HHS K01 MH097972NIMH NIH HHS R01 MH081023NIMH NIH HHS R01 MH101173
6 · The paper itself

Abstract

Autism spectrum disorders (ASDs) are heterogeneous neurodevelopmental conditions. In fMRI studies, including most machine learning studies seeking to distinguish ASD from typical developing (TD) samples, cohorts differing in gender and symptom severity composition are often treated statistically as one "ASD group". Using resting-state functional connectivity (FC) data, we implemented random forest to build diagnostic classifiers in 4 ASD samples including a total of 656 participants (N

Indexed as

Autism diagnostic observation scheduleAutism spectrum disorderConditional random forest Functional connectivityfMRIsymptom severity. machine learning. heterogeneity

Identifiers

PMID34149191
PMCPMC8210842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.