Evidence map›Paper›PMID 34148955›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Spontaneous Regression of Small Cell Lung Carcinoma and Associated Hemichorea.

Koichi Shibata, Yoshiko Nishimura, Hiroshi Sakura

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Koichi ShibataDepartment of Medicine, Tokyo Women's Medical University Medical Center East, Japan.
Yoshiko NishimuraDepartment of Medicine, Tokyo Women's Medical University Medical Center East, Japan.
Hiroshi SakuraDepartment of Medicine, Tokyo Women's Medical University Medical Center East, Japan.
Tokyo Women's Medical University Adachi Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spontaneous regression (SR) of cancer is defined as either partial or complete, and temporary or permanent, disappearance without appropriate treatment for the disease, and this phenomenon is rare in the case of small cell lung carcinoma (SCLC). We herein report an 83-year-old woman who presented with left-sided hemichorea associated with anti-SOX1 (SOX1-Ab) and -CV2/CRMP5 (CV2/CRMP5-Ab) antibodies with SR following a 7-year interval free of disease progression of SCLC. Hemichorea can present with the coexistence of anti-SOX1 and CV2/CRMP5-Ab with SR after a long interval free of SCLC. The immune response associated with these onco-neural antibodies may become independent of the original tumor trigger and remain active for many years.

Indexed as

Lung NeoplasmsSmall Cell Lung CarcinomaAged, 80 and overAutoantibodiesFemaleHumansHydrolasesMicrotubule-Associated ProteinsAutoantibodiesHydrolasesMicrotubule-Associated Proteinsanti-CV2/CRMP5 antibodyanti-SOX antibodychoreaparaneoplastic neurological syndromesmall cell lung carcinomaspontaneous regression

Identifiers

PMID34148955
PMCPMC8710390
OpenAlexW3173775615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.