Evidence map›Paper›PMID 34148627›Full record

ArticleAmerican journal of preventive medicine2021

Temporal Trends in Undervaccination: A Population-Based Cohort Study.

Matthew F Daley, Liza M Reifler, Jo Ann Shoup, Komal J Narwaney, Elyse O Kharbanda, Holly C Groom, Michael L Jackson, Steven J Jacobsen, Huong Q McLean, Nicola P Klein and 4 more

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Matthew F DaleyInstitute for Health Research, Kaiser Permanente Colorado, Aurora, Colorado; Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus Aurora, Colorado. Electronic address: matthew.f.daley@kp.org.
Liza M ReiflerInstitute for Health Research, Kaiser Permanente Colorado, Aurora, Colorado.
Jo Ann ShoupInstitute for Health Research, Kaiser Permanente Colorado, Aurora, Colorado.
Komal J NarwaneyInstitute for Health Research, Kaiser Permanente Colorado, Aurora, Colorado.
Elyse O KharbandaHealthPartners Institute, Minneapolis, Minnesota.
Holly C GroomCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon.
Michael L JacksonKaiser Permanente Washington Health Research Institute, Seattle, Washington.
Steven J JacobsenKaiser Permanente Southern California, Pasadena, California.
Huong Q McLeanMarshfield Clinic Research Institute, Marshfield, Wisconsin.
Nicola P KleinKaiser Permanente Vaccine Study Center, Oakland, California.
Joshua T B WilliamsDepartment of General Pediatrics, Denver Health and Hospitals, Denver, Colorado.
Eric S WeintraubImmunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Michael M McNeilImmunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jason M GlanzInstitute for Health Research, Kaiser Permanente Colorado, Aurora, Colorado; Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionMonitoring the trends in undervaccination, including that because of parental vaccine refusal or delay, can inform public health responses directed at improving vaccine confidence and vaccination coverage.

methodsA retrospective cohort study was conducted in the Vaccine Safety Datalink. The cohort included all children born in 2004-2017 with ≥3 well-child visits between ages 2 and 23 months. Using electronic health record-based vaccination data, the average days undervaccinated was calculated for each child. Undervaccination patterns were assessed through age 23 months. Temporal trends were inspected for inflection points and were analyzed using linear regression. Nested within the cohort study, a survey was conducted to compare parent reports of vaccine refusal or delay with observed vaccination patterns. Data were analyzed in 2020.

resultsThe study cohort consisted of 808,170 children. The percentage of children with average days undervaccinated=0 (fully vaccinated, no delays) rose from a nadir of 47.1% for the birth year 2008 to 68.4% for the birth year 2017 (p

conclusionsIn a 14-year cohort study, vaccination timeliness has improved. However, the small but increasing number of children who received no vaccines by age 23 months warrants additional attention.

Indexed as

MeaslesAdolescentChildChild, PreschoolCohort StudiesHumansInfantRetrospective StudiesVaccinationVaccination Coverage

Identifiers

PMID34148627
PMCPMC8899861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.