Evidence map›Paper›PMID 34148363›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Pro Re Nata Antihypertensive Medications and Adverse Outcomes in Hospitalized Patients: A Propensity-Matched Cohort Study.

Rajesh Mohandas, Gajapathiraju Chamarthi, Shahab Bozorgmehri, Jeremy Carlson, Tezcan Ozrazgat-Baslanti, Rupam Ruchi, Ashutosh Shukla, Amir Kazory, Azra Bihorac, Muna Canales and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Updates in the 2025 AHA/ACC Hypertension Guideline.Current hypertension reports · 2026
    Review
  8. Article
  9. Review
  10. Hypertensive crisis in the critically ill.Annals of intensive care · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Blood pressure elevations in hospital.Australian prescriber · 2022
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Rajesh MohandasDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Gajapathiraju ChamarthiDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Shahab BozorgmehriDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Jeremy CarlsonDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Tezcan Ozrazgat-BaslantiDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Rupam RuchiDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Ashutosh ShuklaDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Amir KazoryDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Azra BihoracDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Muna CanalesDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Mark S SegalDivision of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville (R.M., G.C., S.B., J.C., T.O.-B., R.R., A.S., A.K., A.B., M.C., M.S.S.).
Hypertension Institute · USNorth Florida/South Georgia Veterans Health System · USUnited States Department of Veterans Affairs · US

Funding

Vascular Smooth Muscle Lysyl Oxidase Mediated Increase in Vessel Stiffness and its Effect on Rho-Kinase Mechanosensors: A Novel Mechanism of Atherosclerosis in Chronic Kidney Disease?K08HL130945 · NHLBI · UNIVERSITY OF FLORIDA · PI MOHANDAS, RAJESH · 2016 to 2021
$826k
NHLBI NIH HHS K08 HL130945
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Acute Kidney InjuryAdultAgedAged, 80 and overAntihypertensive AgentsBlood PressureFemaleHospitalizationHumansHypertensionHypotensionIschemic StrokeMaleMiddle AgedAntihypertensive Agentsacute kidney injuryhigh blood pressurehypertensionhypotensionischemic strokemorbiditymortality

Identifiers

PMID34148363
PMCPMC8266743
OpenAlexW3176329798

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.