Evidence map›Paper›PMID 34148174›Full record

SynthesisSleep & breathing = Schlaf & Atmung2022

Obstructive sleep apnea and the risk of mortality in patients with lung cancer: a meta-analysis.

Meng-Xue Chen, Li-Da Chen, Ai-Ming Zeng, Xue-Jun Lin, Jian-Chai Huang, Jie-Feng Huang, Guo-Xiang Lai, Qi-Chang Lin

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
  2. Cancer and obstructive sleep apnea.Chinese medical journal · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Meng-Xue Chen *Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, People's Republic of China.
Li-Da Chen *Department of Respiratory and Critical Care Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian Province, People's Republic of China.
Ai-Ming Zeng *Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, People's Republic of China.
Xue-Jun LinDepartment of Laboratory Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian Province, People's Republic of China.
Jian-Chai HuangDepartment of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, People's Republic of China.
Jie-Feng HuangDepartment of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, People's Republic of China.
Guo-Xiang LaiDepartment of Respiratory and Critical Care Medicine, 900Th Hospital of the Joint Logistics Support Force, Fuzhou General Hospital of Fujian Medical University, Dongfang Hospital of Xiamen University, Fuzhou, People's Republic of China.
Qi-Chang LinDepartment of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, People's Republic of China. chang4e@126.com.ORCID 0000-0003-3081-8084
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrior reports have examined the relationship between obstructive sleep apnea (OSA) and the mortality rate of lung cancer. However, the findings remain controversial. The present meta-analysis was performed to assess the relationship between OSA and increased risk of mortality in patients with lung cancer.

methodsPubMed, Web of Science, and Embase were systematically searched for the correlative studies. Data were analyzed and pooled to evaluate odds ratios (ORs) of lung cancer mortality related to OSA.

resultsFrom 249 identified studies, 3 met inclusion criteria and were analyzed, including 67 patients with lung cancer and comorbid OSA and 45 patients with lung cancer and no OSA. The meta-analysis indicated that OSA was not significantly correlated with mortality rate in lung cancer (OR = 2.005, 95% CI = 0.703 to 5.715, z = 1.30, p = 0.193). There was no significant publication bias according to Begg's tests (p = 0.296) and Egger's tests (p = 0.097).

conclusionThis meta-analysis suggests that OSA is not significantly correlated with the mortality rate in lung cancer.

Indexed as

Lung NeoplasmsSleep Apnea, ObstructiveComorbidityHumansOdds RatioAdultLung cancerMeta-analysisMortalityObstructive sleep apneaOutcome

Identifiers

PMID34148174
OpenAlexW3174540091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.