Evidence map›Paper›PMID 34148055›Full record

ArticleLeukemia2022

Combined analysis of IGHV mutations, telomere length and CD49d identifies long-term progression-free survivors in TP53 wild-type CLL treated with FCR-based therapies.

Andrea G S Pepper, Antonella Zucchetto, Kevin Norris, Erika Tissino, Jerry Polesel, Zarni Soe, David Allsup, Anna Hockaday, Pei Loo Ow, Peter Hillmen and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Leukemia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Andrea G S Pepper *Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.ORCID http://orcid.org/0000-0001-9795-1280
Antonella Zucchetto *Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Kevin NorrisDivision of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.ORCID http://orcid.org/0000-0002-6448-8696
Erika TissinoClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Jerry PoleselUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.ORCID http://orcid.org/0000-0001-9381-1520
Zarni SoeLeeds Teaching Hospital Trust, Leeds, United Kingdom.
David AllsupHull York Medical School, University of Hull, Hull, United Kingdom.ORCID http://orcid.org/0000-0001-6159-6109
Anna HockadayClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom.
Pei Loo OwClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom.
Peter HillmenSection of Experimental Haematology, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom.
Andrew RawstronSection of Experimental Haematology, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom.
Daniel CatovskyInstitute of Cancer Research, Sutton, United Kingdom.ORCID http://orcid.org/0000-0001-6421-1075
Pietro BulianClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Riccardo BombenClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Duncan M BairdDivision of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.ORCID http://orcid.org/0000-0001-8408-5467
Christopher D FeganDivision of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.
Valter GatteiClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.ORCID http://orcid.org/0000-0001-5933-9680
Chris PepperBrighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom. c.pepper@bsms.ac.uk.ORCID http://orcid.org/0000-0003-3603-8839
Centro di Riferimento Oncologico · ITUniversity of Leeds · GBCardiff University · GBBrighton and Sussex Medical School · GBInstitute of Cancer Research · GBLeeds Teaching Hospitals NHS Trust · GBUniversity of Hull · GB

Funding

Cancer Research UK 25447Cancer Research UK 29202Department of HealthMedical Research Council MR/V009095/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationTelomere HomeostasisAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorCyclophosphamideFollow-Up StudiesHumansImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionIntegrin alpha4Leukemia, Lymphocytic, Chronic, B-CellNeoplasm Recurrence, LocalPrognosisRituximabSurvival RateTumor Suppressor Protein p53Biomarkers, TumorCyclophosphamidefludarabineImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionIntegrin alpha4RituximabTP53 protein, humanTumor Suppressor Protein p53Vidarabine

Identifiers

PMID34148055
PMCPMC8727296
OpenAlexW3175849362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.