Evidence map›Paper›PMID 34148032›Full record

ArticleAging2021

Identification and validation of inferior prognostic genes associated with immune signatures and chemotherapy outcome in acute myeloid leukemia.

Jie Wang, Jian-Ping Hao, Md Nazim Uddin, Yun Wu, Rong Chen, Dong-Feng Li, Dai-Qin Xiong, Nan Ding, Jian-Hua Yang, Xuan-Sheng Ding

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  4. miR-379-5p Inhibited the Proliferation of Acute Myeloid Leukemia Cells Through Negative Regulation ofTurkish journal of haematology : official journal of Turkish Society of Haematology · 2025
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  10. Transcriptome Analysis in Mexican Adults with Acute Lymphoblastic Leukemia.International journal of molecular sciences · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jie WangSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Jian-Ping HaoDepartment of Hematology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Md Nazim UddinSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Yun WuDepartment of General Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Rong ChenDepartment of Hematology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Dong-Feng LiDepartment of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Dai-Qin XiongDepartment of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Nan DingDepartment of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Jian-Hua YangDepartment of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Xuan-Sheng DingSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Xinjiang Medical University · CNFirst Affiliated Hospital of Xinjiang Medical University · CNChina Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is a group of heterogeneous hematological malignancies. We identified key genes as

Indexed as

Gene Expression ProfilingGene Expression Regulation, LeukemicFemaleGene OntologyGene Regulatory NetworksGenes, EssentialHumansLeukemia, Myeloid, AcuteMaleMiddle AgedPrognosisProtein Interaction MapsReproducibility of ResultsRNA, Long NoncodingRNA, MessengerROC CurveRNA, Long NoncodingRNA, Messengeracute myeloid leukaemiaimmune infiltrationkey genessurvival prognosisweighted gene co-expression network analysis

Identifiers

PMID34148032
PMCPMC8266366
OpenAlexW3174482058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.