Evidence map›Paper›PMID 34147889›Full record

ArticleSeizure2021

EPM2A in-frame deletion slows neurological decline in Lafora Disease.

Lysa Boissé Lomax, Brandy Verhalen, Berge A Minassian

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Seizure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Lysa Boissé LomaxDepartment of Medicine, Division of Neurology, Kingston Health Sciences Centre, Queen's University, 94 Stuart Street, Kingston, ON, K7L 3N6, Canada.
Brandy VerhalenDepartment of Pediatrics-Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9063, United States.
Berge A MinassianDepartment of Pediatrics-Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9063, United States. Electronic address: berge.minassian@utsouthwestern.edu.
Queen's University · CASouthwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

Suppressing glycogen storage with small molecule inhibitors as a therapeutic approach to Lafora DiseaseP01NS097197 · NINDS · UNIVERSITY OF KENTUCKY · PI GAO, TIANYAN · 2016 to 2021
$9.0M
NINDS NIH HHS P01 NS097197
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lafora DiseaseHumansMutationProtein Tyrosine Phosphatases, Non-ReceptorSequence DeletionEPM2A protein, humanProtein Tyrosine Phosphatases, Non-ReceptorLafora diseaseLaforinProgressive myoclonus epilepsy

Identifiers

PMID34147889
PMCPMC8434975
OpenAlexW3166879037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.