Evidence map›Paper›PMID 34147629›Full record

ReviewNeuroImage2021

Meaningful associations in the adolescent brain cognitive development study.

Anthony Steven Dick, Daniel A Lopez, Ashley L Watts, Steven Heeringa, Chase Reuter, Hauke Bartsch, Chun Chieh Fan, David N Kennedy, Clare Palmer, Andrew Marshall and 14 more

Abstract readReview
In one paragraph

Review in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. From adolescence to Alzheimer's: a neurodevelopmental lifespan model of cognitive vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Anthony Steven DickDepartment of Psychology and Center for Children and Families, Florida International University, Miami, FL, United States.
Daniel A LopezDivision of Epidemiology, Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY 14642, United States.
Ashley L WattsDepartment of Psychology, University of Missouri, MO, United States.
Steven HeeringaInstitute for Social Research, University of Michigan, Ann Arbor, MI 48109, United States.
Chase ReuterHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA 92093, United States.
Hauke BartschMohn Medical Imaging and Visualization Center, Department of Radiology, Haukeland University Hospital, Bergen, Norway.
Chun Chieh FanPopulation Neuroscience and Genetics Lab, University of California, San Diego, La Jolla, CA 92093, United States.
David N KennedyDepartment of Psychiatry, University of Massachusetts Medical School, MA United States, 01604.
Clare PalmerCenter for Human Development, University of California, San Diego, La Jolla, CA 92093, United States.
Andrew MarshallChildren's Hospital Los Angeles, and the Department of Pediatrics, University of Southern California, Los Angeles, CA, United States.
Frank HaistDepartment of Radiology, University of California, San Diego, La Jolla, CA 92093, United States.
Samuel HawesDepartment of Psychology and Center for Children and Families, Florida International University, Miami, FL, United States.
Thomas E NicholsOxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Deanna M BarchDepartments of Psychological & Brain Sciences, Psychiatry and Radiology, Washington University, St. Louis, MO 63130, United States.
Terry L JerniganDepartment of Psychiatry, University of Massachusetts Medical School, MA United States, 01604.
Hugh GaravanDepartment of Psychiatry, University of Vermont, Burlington, VT, 05405, United States.
Steven GrantBehavioral and Cognitive Neuroscience Branch, Division of Neuroscience and Behavior, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States.
Vani PariyadathBehavioral and Cognitive Neuroscience Branch, Division of Neuroscience and Behavior, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States.
Elizabeth HoffmanNational Institute on Drug Abuse, National Institutes of Health, Department of Heatlh and Human Services, Bethesda, MD, United States.
Michael NealeDepartment of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, United States.
Elizabeth A StuartDepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Martin P PaulusLaureate Institute for Brain Research, Tulsa, OK, United States.
Kenneth J SherDepartment of Psychology, University of Missouri, MO, United States.
Wesley K ThompsonHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA 92093, United States; Population Neuroscience and Genetics Lab, University of California, San Diego, La Jolla, CA 92093, United States. Electronic address: wkthompson@health.ucsd.edu.

Funding

ABCD-USA Consortium: Coordinating CenterU24DA041147 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, TERRY L. JERNIGAN · 2015 to 2026
$54.7M
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5M
Adolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5M
ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Prospective Research Studies of Maturation (PRISM)- Research ProjectU01DA041134 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ERIN MCGLADE, PERRY FRANKLIN RENSHAW · 2015 to 2026
$29.2M
ABCD-USA CONSORTIUM: RESEARCH PROJECTU01DA041048 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Megan Marie Herting, ELIZABETH R SOWELL · 2015 to 2026
$28.7M
ABCD-USA Consortium: Research ProjectU01DA041106 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mary M Heitzeg, Chandra Sekhar Sripada · 2015 to 2026
$24.9M
FIU-ABCD: Pathways and Mechanisms to Addiction in the Latino Youth of South FloridaU01DA041156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez, Angela R Laird · 2015 to 2026
$22.8M
ABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3M
ABCD-USA: NYC Research ProjectU01DA041174 · NIDA · YALE UNIVERSITY · PI Arielle Ryan Baskin-Sommers, Betty J Casey · 2015 to 2026
$19.7M
Adolescent Brain Cognitive Development (ABCD) Prospective Research in Studies of Maturation (PRISM) ConsortiumU01DA041117 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LINDA CHANG, THOMAS M ERNST · 2015 to 2026
$19.5M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
NICHD NIH HHS P50 HD103525NIDA NIH HHS U01 DA041022NIDA NIH HHS U01 DA041025NIDA NIH HHS U01 DA041028NIDA NIH HHS U01 DA041048NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041093NIDA NIH HHS U01 DA041106NIDA NIH HHS U01 DA041117NIDA NIH HHS U01 DA041120NIDA NIH HHS U01 DA041134NIDA NIH HHS U01 DA041148NIDA NIH HHS U01 DA041156NIDA NIH HHS U01 DA041174NIDA NIH HHS U01 DA050987NIDA NIH HHS U01 DA050988NIDA NIH HHS U01 DA050989NIDA NIH HHS U01 DA051016NIDA NIH HHS U01 DA051018NIDA NIH HHS U01 DA051037NIDA NIH HHS U01 DA051038NIDA NIH HHS U01 DA051039NIDA NIH HHS U24 DA041123NIDA NIH HHS U24 DA041147
6 · The paper itself

Abstract

The Adolescent Brain Cognitive Development (ABCD) Study is the largest single-cohort prospective longitudinal study of neurodevelopment and children's health in the United States. A cohort of n = 11,880 children aged 9-10 years (and their parents/guardians) were recruited across 22 sites and are being followed with in-person visits on an annual basis for at least 10 years. The study approximates the US population on several key sociodemographic variables, including sex, race, ethnicity, household income, and parental education. Data collected include assessments of health, mental health, substance use, culture and environment and neurocognition, as well as geocoded exposures, structural and functional magnetic resonance imaging (MRI), and whole-genome genotyping. Here, we describe the ABCD Study aims and design, as well as issues surrounding estimation of meaningful associations using its data, including population inferences, hypothesis testing, power and precision, control of covariates, interpretation of associations, and recommended best practices for reproducible research, analytical procedures and reporting of results.

Indexed as

Adolescent DevelopmentPsychology, AdolescentAdolescentAlcoholismBrainCatchment Area, HealthChildCognitionFemaleFollow-Up StudiesGene-Environment InteractionHumansMaleModels, NeurologicalModels, PsychologicalOrgan SizeAdolescent brain cognitive development studyCovariate AdjustmentsEffect SizesGeneticsHypothesis testingPopulation neuroscienceReproducibility

Identifiers

PMID34147629
PMCPMC8803401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.