Evidence map›Paper›PMID 34146837›Full record

ArticleNuclear medicine and biology

Labeling single domain antibody fragments with

Zhengyuan Zhou, Darryl McDougald, Rebecca Meshaw, Irina Balyasnikova, Michael R Zalutsky, Ganesan Vaidyanathan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nuclear medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Radiosynthesis and preclinical evaluations of [American journal of nuclear medicine and molecular imaging · 2024
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhengyuan ZhouDepartment of Radiology, Duke University Medical Center, Durham, NC, USA.
Darryl McDougaldDepartment of Radiology, Duke University Medical Center, Durham, NC, USA.
Rebecca MeshawDepartment of Radiology, Duke University Medical Center, Durham, NC, USA.
Irina BalyasnikovaThe Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Michael R ZalutskyDepartment of Radiology, Duke University Medical Center, Durham, NC, USA.
Ganesan VaidyanathanDepartment of Radiology, Duke University Medical Center, Durham, NC, USA. Electronic address: ganesan.v@duke.edu.
Duke Medical Center · USNorthwestern University · US

Funding

RADIOTHERAPY USING MONOCLONAL ANTIBODIES AND ASTATINER01CA042324 · NCI · DUKE UNIVERSITY · PI ZALUTSKY, MICHAEL ROD · 1985 to 2020
$4.6M
ASTATINE AND IODINE RADIOLABELED MONOCLONAL ANTIBODIESR37CA042324 · NCI · DUKE UNIVERSITY · PI ZALUTSKY, MICHAEL ROD · 1999 to 2008
$3.8M
Labeling nanobodies with 18F residualizing labels for HER2 specific PET imagingR01CA188177 · NCI · DUKE UNIVERSITY · PI VAIDYANATHAN, GANESAN · 2015 to 2019
$1.8M
NCI NIH HHS R01 CA042324NCI NIH HHS R01 CA188177NCI NIH HHS R37 CA042324
6 · The paper itself

Abstract

introductionLabeling single domain antibody fragments (sdAbs) with

methods[

resultsRadiochemical yields for the synthesis of Boc

conclusionsAlthough higher radiochemical yields than that reported for [

Indexed as

BenzoatesFluorine RadioisotopesIsotope LabelingSingle-Domain AntibodiesAnimalsCell Line, TumorFemaleHumansMiceRadiochemistryTissue DistributionTriazolesBenzoatesFluorine-18Fluorine RadioisotopesSingle-Domain AntibodiesTriazolesBreast cancerFluorine-18HER2NanobodySingle domain antibody fragment

Identifiers

PMID34146837
PMCPMC8448961
OpenAlexW3168686383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.