SynthesisInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021
Association of Lung Ultrasound Score with Mortality and Severity of COVID-19: A Meta-Analysis and Trial Sequential Analysis.
Synthesis in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05631756 ("Correlation Between PaO2/FiO2 and Lung Ultrasound Score in Patients Admitted to an Intensive Care Unit With Interstitial Syndrome), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
"Correlation Between PaO2/FiO2 and Lung Ultrasound Score in Patients Admitted to an Intensive Care Unit With Interstitial Syndrome: A Prospective Physiological Study"
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Lung ultrasound score and in-hospital mortality of adults with acute respiratory distress syndrome: a meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Lung ultrasound score severity cut-off points in COVID-19 pneumonia. A systematic review and validating cohort.Medicina clinica · 2023Pooled it
- Interpretable machine learning model based on multimodal ultrasound for bedside diagnosis of acute exacerbations in COPD.Respiratory research · 2025Article
- Association of lung ultrasound score with 72-hour intubation needs in pneumonia patients presenting to the emergency department.BMC emergency medicine · 2025Observational
- Thoracic Ultrasound for Acute Dyspnea in Interstitial Lung Disease.Journal of clinical medicine · 2025Article
- Lung ultrasound for the diagnosis and monitoring of pneumonia in a tuberculosis-endemic setting: a prospective study.BMJ open · 2025Article
- Lung ultrasound score predicts outcomes in patients with acute respiratory failure secondary to COVID-19 treated with non-invasive respiratory support: a prospective cohort study.The ultrasound journal · 2024Article
- Sonographic Aeration Scoring Indicates Disease Severity in Critically Ill Patients with COVID-19.Diagnostics (Basel, Switzerland) · 2023Article
- Lung ultrasound score severity cut-off points in COVID-19 pneumonia. A systematic review and validating cohort.Medicina clinica (English ed.) · 2023Article
- CORONA (COre ultRasOund of covid in iNtensive care and Acute medicine) study: National service evaluation of lung and heart ultrasound in intensive care patients with suspected or proven COVID-19.Journal of the Intensive Care Society · 2023Article
- Point-of-care Lung Ultrasound, Lung CT and NEWS to Predict Adverse Outcomes and Mortality in COVID-19 Associated Pneumonia.Journal of intensive care medicine · 2022Article
- Correlation between hypoxaemia and lung ultrasound score in patients presenting to an emergency department with interstitial syndrome: a prospective physiological study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2022Article
- Use of POCUS in Chest Pain and Dyspnea in Emergency Department: What Role Could It Have?Diagnostics (Basel, Switzerland) · 2022Review
- A Pilot Study of the Efficacy and Economical Sustainability of Acute Coronavirus Disease 2019 Patient Management in an Outpatient Setting.Frontiers in medicine · 2022Article
- Observational
- Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort.Diagnostics (Basel, Switzerland) · 2021Article
- Lung Ultrasound and High-Resolution Computed Tomography in Suspected COVID-19 Patients Admitted to the Emergency Department: A Comparison.Journal of diagnostic medical sonography : JDMSArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe coronavirus disease 2019 (COVID-19) pandemic has rapidly spread all over the world. Lung ultrasound (LUS) has emerged as a useful tool for diagnosing many respiratory diseases. The prognostic role of LUS in COVID-19 patients has not yet been established.
methodsSeveral databases were searched on 09 April 2021. The difference in LUS score between the death and survival groups, and the relationship between LUS score and COVID-19 severity were both assessed.
resultsThe LUS score was significantly higher in the death group compared with the survival group (weighted mean difference (WMD) = 8.21, 95% CI: 4.74-11.67, P < 0.001), which was confirmed by trial sequential analysis. Those with mild/moderate, severe and critical COVID-19 had a progressively higher LUS score (critical vs. severe: WMD = 8.78, 95% CI: 4.17-13.38; P < 0.001; critical vs. mild/moderate/severe: WMD = 10.00, 95% CI: 6.83-13.17, P < 0.001; severe vs. moderate: WMD = 5.96, 95% CI: 3.48-8.44, P < 0.001; severe vs. mild/moderate: WMD = 7.31, 95% CI: 4.45-10.17, P < 0.001).
conclusionsThe LUS score was associated with mortality and severity of COVID-19. The LUS score might be a risk stratification tool for COVID-19 patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.