ArticlePharmacological reports : PR2021
Maternal feeding patterns affect the offspring's brain: focus on serotonin 5-HT
Article in Pharmacological reports : PR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Single ayahuasca administration mitigates long-term behavioral and neurochemical effects of early-life stress in rats.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Maternal Obesity in Pregnancy: Risk Factor for Neurodevelopmental Outcomes in Offspring.Journal of neurochemistry · 2025Review
- The Influence of Maternal Metabolic State and Nutrition on Offspring Neurobehavioral Development: A Focus on Preclinical Models.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Review
- Maternal Metabolic State and Fetal Sex and Genotype Modulate Methylation of the Serotonin Receptor Type 2A Gene (Biomedicines · 2022Article
- Perinatal Western-style diet alters serotonergic neurons in the macaque raphe nuclei.Frontiers in neuroscience · 2022Article
- FumDSB Can Reduce the Toxic Effects of Fumonisin BToxins · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRecent studies have shown a relationship between the composition of the maternal diet and acquiring a risk of mental illnesses through changes in the offspring's brain. This study assessed the role of a modified maternal diet on the levels of serotonin (5-HT)
methodsWistar rat dams during gestation and lactation were maintained either on a standard (SD) or special diets: high-fat (HFD), high-carbohydrate (rich in sucrose, HCD) or mixed (MD). Offspring were weaned to SD after lactation, and at postnatal days (PNDs) 28 and 63 changes in the 5-HT
resultsMaternal HFD reduced the expression of 5-HT
conclusionOur findings indicate that a modified maternal diet induces age- and sex-specific adaptive changes mainly in 5-HT
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Registered trials
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