SynthesisMedicine, health care, and philosophy2021
Ethical issues in biomedical research using electronic health records: a systematic review.
Synthesis in Medicine, health care, and philosophy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Revolutionizing sepsis diagnosis using machine learning and deep learning models: a systematic literature review.BMC infectious diseases · 2025Pooled it
- The Ethics of Leveraging Routinely Collected Patient Data for AI Development: Mixed Methods Study.Journal of medical Internet research · 2026Article
- Implementing broad consent for research with routinely collected clinical data and residual biosamples in a cancer hospital: using mixed methods approach to evaluate consent rates and patients' perspectives.BMC medical ethics · 2026Article
- The INTEGRITY guidelines - ethical guidance for research involving deceased donation and transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Perceived clinical and ethical impact of digital transformation in healthcare and research: A survey in the MENA region.PloS one · 2025Article
- Proxy measures for the assessment of psychotic and affective symptoms in studies using electronic health records.BJPsych open · 2024Article
- Article
- Health Research with Data in a Time of Privacy: Which Information do Patients Want?Journal of empirical research on human research ethics : JERHRE · 2023Article
- Digital Transformation in Healthcare: Technology Acceptance and Its Applications.International journal of environmental research and public health · 2023Article
- Preclinical Alzheimer Disease and the Electronic Health Record: Balancing Confidentiality and Care.Neurology · 2022Article
- Ownership of individual-level health data, data sharing, and data governance.BMC medical ethics · 2022Article
- Who tweets what about personalised medicine? Promises and concerns from Twitter discussions in Denmark.Digital healthArticle
- Generating fit-for-purpose real-world evidence in Asia: How far are we from closing the gaps?Perspectives in clinical researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Digitization of a health record changes its accessibility. An electronic health record (EHR) can be accessed by multiple authorized users. Health information from EHRs contributes to learning healthcare systems' development. The objective of this systematic review is to answer a question: What are ethical issues concerning research using EHRs in the literature? We searched Medline Ovid, Embase and Scopus for publications concerning ethical issues of research use of EHRs. We employed the constant comparative method to retrieve common ethical themes. We descriptively summarized empirical studies. The study reveals the breadth, depth, and complexity of ethical problems associated with research use of EHRs. The central ethical question that emerges from the review is how to manage access to EHRs. Managing accessibility consists of interconnected and overlapping issues: streamlining research access to EHRs, minimizing risk, engaging and educating patients, as well as ensuring trustworthy governance of EHR data. Most of the ethical problems concerning EHR-based research arise from rapid cultural change. The framing of concepts of privacy, as well as individual and public dimensions of beneficence, are changing. We are currently living in the middle of this transition period. Human emotions and mental habits, as well as laws, are lagging behind technological developments. In the medical tradition, individual patient's health has always been in the center. Transformation of healthcare care, its digitalization, seems to have some impacts on our perspective of health care ethics, research ethics and public health ethics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.