Evidence map›Paper›PMID 34146195›Full record

ArticleNeurochemical research2021

SRY-Box 21 Antisense RNA 1 Knockdown Diminishes Amyloid Beta

Fengming Gu, Daofei Ji, Hongzao Ni, Depeng Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. BetaZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
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  8. Article
  9. Expression of Linear and Circular lncRNAs in Alzheimer's Disease.Journal of molecular neuroscience : MN · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fengming Gu *Department of Intensive Care Unit, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, 223002, China.
Daofei Ji *Department of Neurosurgery, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221006, China.
Hongzao NiDepartment of Neurosurgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, 223002, China.
Depeng ChenDepartment of Intensive Care Unit, People's Hospital of Huai'an Hongze District, 102 Dongfeng Road, Huai'an, 223100, China. chenbbmc@163.com.
Second People’s Hospital of Huai’an · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aimed to explore the function and mechanism of action of long noncoding RNA (lncRNA) SRY-Box 21 antisense RNA 1 (SOX21-AS1) in amyloid beta

Indexed as

Amyloid beta-PeptidesApoptosisCell LineCell SurvivalGene SilencingHumansMicroRNAsNeuronsOxidative StressPeptide FragmentsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRNA, Long NoncodingSignal TransductionUp-RegulationAmyloid beta-Peptidesamyloid beta-protein (25-35)MicroRNAsMIRN132 microRNA, humanPeptide FragmentsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRNA, Long NoncodingAlzheimer’s diseaseAmyloid betamiR-132PI3K/AKT pathwaySOX21-AS1

Identifiers

PMID34146195
OpenAlexW3168545494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.