Evidence map›Paper›PMID 34146146›Full record

ArticleArchives of gynecology and obstetrics2021

Fishbone double-layer barbed suture in cesarean section: a help in preventing long-term obstetric sequelae?

Franco Alessandri, Giulio Evangelisti, Maria Grazia Centurioni, Claudio Gustavino, Simone Ferrero, Fabio Barra

3 registry-linked trialsAbstract readNews
PubMed Publisher
In one paragraph

Article in Archives of gynecology and obstetrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04825821 completednot on this map

A Prospective Pilot Study Comparing Incidence and Characteristics of Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture

TypeobservationalSponsorOspedale Policlinico San MartinoRan2019 to 2022Enrolled247ConditionsIsthmocele, Uterine Scar Defects, Cesarean Section Complications, Uterine NicheArmsClinical and ultrasonographic assessment
NCT05166174 completednot on this map

Lower Uterine Segment at the Next Pregnancy Following a Cesarean Section With Barbed Suture: an Observational Prospective Comparative Study

TypeobservationalSponsorPiazza della Vittoria 14 Studio Medico - Ginecologia e OstetriciaRan2019 to 2021Enrolled93ConditionsCesarean Wound, Dehiscence, Cesarean Section ComplicationsArmsTransvaginal ultrasound in the third trimester pregnancy
NCT05750394 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Cesarean 123 Trial: Prospective Randomized Trial Comparing Single, Double and Triple Layer Uterine Closures During Cesarean Delivery

TypeinterventionalSponsorBrigham and Women's HospitalRan2023 to 2025Enrolled120ConditionsPregnancy RelatedArmsUterine layers closed, Suture Type, Endometrium
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Franco AlessandriUnit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.
Giulio EvangelistiUnit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.
Maria Grazia CenturioniUnit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.
Claudio GustavinoUnit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.
Simone FerreroAcademic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy. simone.ferrero@unige.it.ORCID 0000-0003-2225-5568
Fabio BarraUnit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.
Ospedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the high number of cesarean sections over the last two decades, there has been a growing awareness of the post-surgical obstetric long-term sequelae (i.e., uterine scar defects and abnormal placentation) following this surgical procedure. Knotless barbed suture is an absorbable bidirectional and unidirectional monofilament, characterized by the presence of "barbs" along its length. After being introduced in gynecology, the favorable features of the knotless barbed suture, such as the uniform distribution of tensile force, provide the rationale for studying its benefits in obstetric surgery. Recently, our research group has investigated a double-layer barbed suture ("fishbone" suture) for closing the uterine wall during cesarean section by a case-control study, reporting a low incidence of uterine scar defects and a reduced size of defects in women who had developed them (NCT04825821). In the near future, large prospective studies are strongly awaited to investigate reproductive outcomes and long-term sequelae after cesarean section performed with knotless barbed suture.

Indexed as

Suture TechniquesCase-Control StudiesCesarean SectionFemaleHumansPregnancySuturesAbnormal placentationCesarean sectionDouble-layer uterine closureFish bone sutureIsthmoceleKnotless barbed suturePlacenta accreta spectrumUterine scar defects

Identifiers

PMID34146146
OpenAlexW3170176663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.