Evidence map›Paper›PMID 34146035›Full record

ArticleIndian journal of ophthalmology2021

Changes in intraocular pressures associated with inhalational and mixed anesthetic agents currently used in ophthalmic surgery.

Sirisha Senthil, Mamata Nakka, Umashankar Rout, Hasnat Ali, Nikhil Choudhari, Swathi Badakere, Chandrasekhar Garudadri

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Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sirisha SenthilVST Glaucoma Center, L V Prasad Eye Institute, Banjara Hills, Hyderabad, Telangana, India.
Mamata NakkaVST Glaucoma Center, L V Prasad Eye Institute, Banjara Hills, Hyderabad, Telangana, India.
Umashankar RoutDepartment of Anesthesia, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Hasnat AliCenter for Biostatistcs and Epidemiology, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Nikhil ChoudhariVST Glaucoma Center, L V Prasad Eye Institute, Banjara Hills, Hyderabad, Telangana, India.
Swathi BadakereVST Glaucoma Center, L V Prasad Eye Institute, Banjara Hills, Hyderabad, Telangana, India.
Chandrasekhar GarudadriVST Glaucoma Center, L V Prasad Eye Institute, Banjara Hills, Hyderabad, Telangana, India.
L V Prasad Eye Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of this study was to measure changes in intraocular pressures (IOPs) associated with inhalational and mixed anesthetic agents currently used for general anesthesia (GA) in ophthalmic surgery. Methods: In a cross-sectional study, 48 eyes from 48 consecutive subjects that underwent ophthalmic surgery under GA were included. Mixed anesthetics were used in 26 eyes and sevoflurane in 22 eyes. IOPs of the nonsurgery eyes were recorded at T1 (5 min before induction of anesthesia), T2 (5 min after intubation), and T3 (at the conclusion of surgery before extudation) using ICare PRO and Perkins tonometers. Linear mixed-effects models were used to compare differences in IOPs at various time points. Outcome measures were changes in IOP after induction of GA, intubation, and just before extubation and comparisons of decreases in IOPs induced by sevoflurane and mixed anesthetics. Results: Mean preanesthesia IOP for patients in this study (mean age ± standard deviation = 26.9 ± 18.3 years; range: 5-70 years) was 17.9 ± 4.9 (range: 10-30) mm Hg. There was a significant decrease in the mean IOP (standard error (SE) (in mm Hg) at T2 (Perkins: -4.65 (0.57); ICare PRO: -5.16 (0.56) and T3 (Perkins: -5.63; ICare PRO: -5.36) as compared to the IOP at T1 (P < 0.001). The decreases in IOPs at T2 and T3 were similar in both anesthetic groups (T2:P = 0.60; T3: P = 0.33). Conclusion: Significant decreases in IOPs after GA were observed and the differences were not significantly different between sevoflurane and mixed anesthetic agents. For management decisions in pediatric glaucoma, the IOP measurements under GA are crucial, the underestimation of IOP as noted with currently used anesthetic agents has to be accounted for and decisions are taken appropriately.

Indexed as

AnestheticsGlaucomaChildCross-Sectional StudiesHumansIntraocular PressureProspective StudiesReproducibility of ResultsTonometry, OcularAnestheticsGeneral anesthesiICare PRO tonometerinhalational anestheticsintraocular pressurePerkins tonometer

Identifiers

PMID34146035
PMCPMC8374814
OpenAlexW3166856767

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.