Evidence map›Paper›PMID 34145738›Full record

ArticleJournal of cellular and molecular medicine2021

Histone deacetylase 9 deficiency exaggerates uterine M2 macrophage polarization.

Yanqin Liu, Meirong Du, Hai-Yan Lin

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

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  15. Deficiency ofFrontiers in immunology · 2022
    Article
  16. Review
  17. Article
  18. Acetylation in Tumor Immune Evasion Regulation.Frontiers in pharmacology · 2021
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Yanqin LiuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-5559-9992
Meirong DuGynecology and Obstetrics Hospital, Fudan University, Shanghai, China.
Hai-Yan LinState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-1623-9361
Anhui University · CNChinese Academy of Sciences · CNObstetrics and Gynecology Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The maternal-foetal interface is an immune-privileged site where the semi-allogeneic embryo is protected from attacks by the maternal immune system. Uterine macrophages are key players in establishing and maintaining pregnancy, and the dysregulation of the M1-M2 subpopulation balance causes abortion. We separated two distinct mouse uterine macrophage subpopulations during early pregnancy, CD45

Indexed as

AnimalsCells, CulturedDisease Models, AnimalFemaleFetusGene Expression ProfilingHistone DeacetylasesLipopolysaccharidesMacrophagesMiceMice, Inbred BALB CPhagocytosisRepressor ProteinsUterusHdac9 protein, mouseHistone DeacetylasesLipopolysaccharidesRepressor Proteinsabortionhistone deacetylase 9macrophage polarizationpregnancyuterine macrophage

Identifiers

PMID34145738
PMCPMC8358884
OpenAlexW3171808984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.