ArticleThe International journal of eating disorders2021
Comorbid mental disorders during long-term course in a nationwide cohort of patients with anorexia nervosa.
Article in The International journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Temporal Trends in the Epidemiology of Eating Disorders Between 2000 and 2022: A Danish Register Study of Their Incidence and Comorbidities.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Anorexia Nervosa and Emotional Dysregulation: A Longitudinal Study on the Characteristics and Clinical Implications in a Group of Female Adolescents.Children (Basel, Switzerland) · 2026Article
- Patterns of Medical Diagnoses Before and After a Diagnosis of Anorexia Nervosa: A Danish Nationwide Cohort Study.The International journal of eating disorders · 2025Article
- An evolutionary perspective on the genetics of anorexia nervosa.Translational psychiatry · 2025Article
- Outcomes in people with eating disorders: a transdiagnostic and disorder-specific systematic review, meta-analysis and multivariable meta-regression analysis.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Predicting long-term outcome in anorexia nervosa: a machine learning analysis of brain structure at different stages of weight recovery.Psychological medicine · 2023Article
- Children's eating attitudes test (ChEAT): validation and reliability in Turkish children.Journal of eating disorders · 2023Article
- Autism diagnosis in females by eating disorder professionals.Journal of eating disorders · 2023Article
- General psychopathological symptoms in children, adolescents, and young adults with anorexia nervosa-a naturalistic study on follow-up and treatment.European journal of pediatrics · 2023Article
- Increased risk of somatic diseases following anorexia nervosa in a controlled nationwide cohort study.The International journal of eating disorders · 2022Article
- Anorexia Nervosa: Reduction in Depression during Inpatient Treatment Is Closely Related to Reduction in Eating Disorder Psychopathology.Journal of personalized medicine · 2022Article
- Comorbidity between eating disorders and psychiatric disorders.The International journal of eating disorders · 2022Article
- Inpatient Weight Restoration Treatment Is Associated with Decrease in Post-Meal Anxiety.Journal of personalized medicine · 2021Article
- Comorbid mental disorders during long-term course in a nationwide cohort of patients with anorexia nervosa.The International journal of eating disorders · 2021Article
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6 authors.
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Abstract
objectiveComorbid mental disorders in anorexia nervosa during long-term course require detailed studies.
methodThis matched cohort study was based on nationwide Danish register data of all patients born 1961-2008 with a first-time ICD-10 diagnosis of anorexia nervosa (AN) between 1994 and 2018 at age 8-32 and matched controls taken from all individuals without an eating disorder (ED). For nine categories of non-eating mental disorders, time from date of first AN-diagnosis (inclusion date) to time of first diagnosis, accounting for censoring, was studied by use of time-stratified Cox models.
resultsA total of 9,985 patients with AN (93.5% females) and 49,351 matched controls were followed for a median (IQR) of 9.0 (4.4-15.7) years. For patients, there was about 25% and 55% risk of receiving any non-ED disorder during the first 2 years and two decades after inclusion, respectively. A hazard ratio (HR) of seven for any non-ED was found for the first 12 months after inclusion, a ratio that reduced to two at five or more years after inclusion. During the first years, large HRs ranging in 6-9 were found for affective, autism spectrum, personality, and obsessive-compulsive disorders with the latter displaying the highest continuous increased risk. The HR at 12 months after inclusion was highest for any non-ED disorder and affective disorders in patients aged 8-13 at diagnosis. DISCUSSION: Comorbid mental disorders in AN are most frequently diagnosed in the first years after diagnosis of AN and on longer terms imply a double immediate risk.
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