Evidence map›Paper›PMID 34145552›Full record

ReviewFolia microbiologica2021

War of the microbial world: Acanthamoeba spp. interactions with microorganisms.

Mohammad Ridwane Mungroo, Ruqaiyyah Siddiqui, Naveed Ahmed Khan

Open access · bronzeAbstract readReview
In one paragraph

Review in Folia microbiologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. The Implication of Horizontal Gene Transfer BetweenPathogens (Basel, Switzerland) · 2026
    Pooled it
  2. Frontiers in immunology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. First report on the long-term viability ofJournal of water and health · 2024
    Article
  13. Article
  14. Isolates ofJournal of water and health · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mohammad Ridwane MungrooDepartment of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Ruqaiyyah SiddiquiCollege of Arts and Sciences, American University of Sharjah, Sharjah, United Arab Emirates.
Naveed Ahmed KhanDepartment of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. naveed5438@gmail.com.ORCID http://orcid.org/0000-0001-7667-8553
University of Sharjah · AEAmerican University of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acanthamoeba is known to interact with a plethora of microorganisms such as bacteria, fungi and viruses. In these interactions, the amoebae can be predatory in nature, transmission vehicle or an incubator. Amoebae consume microorganisms, especially bacteria, as food source to fulfil their nutritional needs by taking up bacteria through phagocytosis and lysing them in phagolysosomes and hence play an eminent role in the regulation of bacterial density in the nature and accountable for eradication of around 60% of the bacterial population in the environment. Acanthamoeba can also act as a "Trojan horse" for microbial transmission in the environment. Additionally, Acanthamoeba may serve as an incubator-like reservoir for microorganisms, including those that are pathogenic to humans, where the microorganisms use amoebae's defences to resist harsh environment and evade host defences and drugs, whilst growing in numbers inside the amoebae. Furthermore, amoebae can also be used as a "genetic melting pot" where exchange of genes as well as adaptation of microorganisms, leading to higher pathogenicity, may arise. Here, we describe bacteria, fungi and viruses that are known to interact with Acanthamoeba spp.

Indexed as

AcanthamoebaBacterial Physiological PhenomenaHost Microbial InteractionsVirus Physiological PhenomenaFungi

Identifiers

PMID34145552
PMCPMC8212903
OpenAlexW3167204574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.