Evidence map›Paper›PMID 34145330›Full record

ArticleScientific reports2021

Prediction of venous thromboembolism with machine learning techniques in young-middle-aged inpatients.

Hua Liu, Hua Yuan, Yongmei Wang, Weiwei Huang, Hui Xue, Xiuying Zhang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hua Liu *China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130000, People's Republic of China.
Hua Yuan *School of Nursing, Jilin University, Changchun, 130021, Jilin, People's Republic of China.
Yongmei WangThe Second Hospital of Jilin University, Changchun, 130000, Jilin, People's Republic of China.
Weiwei HuangChina-Japan Union Hospital of Jilin University, Changchun, Jilin, 130000, People's Republic of China.
Hui XueDepartment of Histology & Embryology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, People's Republic of China. xuehui@jlu.edu.cn.
Xiuying ZhangSchool of Nursing, Jilin University, Changchun, 130021, Jilin, People's Republic of China. z_xy@jlu.edu.cn.
Jilin University · CNSecond Affiliated Hospital of Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating studies appear to suggest that the risk factors for venous thromboembolism (VTE) among young-middle-aged inpatients are different from those among elderly people. Therefore, the current prediction models for VTE are not applicable to young-middle-aged inpatients. The aim of this study was to develop and externally validate a new prediction model for young-middle-aged people using machine learning methods. The clinical data sets linked with 167 inpatients with deep venous thrombosis (DVT) and/or pulmonary embolism (PE) and 406 patients without DVT or PE were compared and analysed with machine learning techniques. Five algorithms, including logistic regression, decision tree, feed-forward neural network, support vector machine, and random forest, were used for training and preparing the models. The support vector machine model had the best performance, with AUC values of 0.806-0.944 for 95% CI, 59% sensitivity and 99% specificity, and an accuracy of 87%. Although different top predictors of adverse outcomes appeared in the different models, life-threatening illness, fibrinogen, RBCs, and PT appeared to be more consistently featured by the different models as top predictors of adverse outcomes. Clinical data sets of young and middle-aged inpatients can be used to accurately predict the risk of VTE with a support vector machine model.

Indexed as

InpatientsMachine LearningAdolescentAdultArea Under CurveDisease ManagementDisease SusceptibilityFemaleHumansMaleMiddle AgedPrognosisSupport Vector MachineVenous ThromboembolismYoung Adult

Identifiers

PMID34145330
PMCPMC8213829
OpenAlexW3169209137

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.