Evidence map›Paper›PMID 34145289›Full record

ArticleNature communications2021

Association of social distancing and face mask use with risk of COVID-19.

Sohee Kwon, Amit D Joshi, Chun-Han Lo, David A Drew, Long H Nguyen, Chuan-Guo Guo, Wenjie Ma, Raaj S Mehta, Fatma Mohamed Shebl, Erica T Warner and 11 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
24.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.

  1. Pooled it
  2. COVID-19 Prevention Behaviors and Mistrust Among Black and Latino Public Housing Residents in NYC.Health education & behavior : the official publication of the Society for Public Health Education · 2026
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 3 countries.

Sohee Kwon *Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Amit D Joshi *Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Chun-Han LoClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8202-4513
David A DrewClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Long H NguyenClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5436-4219
Chuan-Guo GuoClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0657-473X
Wenjie MaClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Raaj S MehtaClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Fatma Mohamed SheblMedical Practice Evaluation Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Erica T WarnerClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Christina M AstleyDivision of Endocrinology and Computational Epidemiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5063-8470
Jordi MerinoDiabetes Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-8312-1438
Benjamin MurraySchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Jonathan WolfZoe Limited, London, UK.ORCID 0000-0002-0530-2257
Sebastien OurselinSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Claire J StevesDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Tim D SpectorDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.ORCID 0000-0002-9795-0365
Jaime E HartChanning Division of Network Medicine, Department of Medicine, Brigham and Hospital and Harvard Medical School, Boston, MA, USA.
Mingyang SongClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Trang VoPhamEpidemiology Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Andrew T ChanClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. achan@mgh.harvard.edu.ORCID 0000-0001-7284-6767
Harvard University · USKing's College London · GBBroad Institute · USBrigham and Women's Hospital · USCenter for Disease Dynamics, Economics & Policy · USUniversity of Washington · USZOE (United Kingdom) · GB

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Risk Prediction of Symptomatic Gallbladder DiseaseK01DK110267 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI JOSHI, AMIT DOLAR · 2016 to 2021
$876k
Impact of Aspirin on the Gut Microbiome and Mucosal MicroenvironmentK01DK120742 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI DREW, DAVID A · 2020 to 2024
$793k
Air pollution and health disparities in liver disease and cancerK01DK125612 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VOPHAM, TRANG · 2020 to 2024
$746k
Seasonal and Viral Determinants of Type 1 Diabetes Onset, Remission, and Glycemic ControlK23DK120899 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI ASTLEY, CHRISTINA M. · 2019 to 2021
$682k
Department of Health NIHR300159EPA EP-W-17-011Medical Research Council MR/M016560/1NIDDK NIH HHS K01 DK110267NIDDK NIH HHS K01 DK120742NIDDK NIH HHS K01 DK125612NIDDK NIH HHS K23 DK120899NIDDK NIH HHS P30 DK040561NIEHS NIH HHS P30 ES000002Wellcome TrustWellcome Trust T213038/Z/18/ZWellcome Trust WT203148/Z/16/ZWellcome Trust WT212904/Z/18/Z
6 · The paper itself

Abstract

Given the continued burden of COVID-19 worldwide, there is a high unmet need for data on the effect of social distancing and face mask use to mitigate the risk of COVID-19. We examined the association of community-level social distancing measures and individual face mask use with risk of predicted COVID-19 in a large prospective U.S. cohort study of 198,077 participants. Individuals living in communities with the greatest social distancing had a 31% lower risk of predicted COVID-19 compared with those living in communities with poor social distancing. Self-reported 'always' use of face mask was associated with a 62% reduced risk of predicted COVID-19 even among individuals living in a community with poor social distancing. These findings provide support for the efficacy of mask-wearing even in settings of poor social distancing in reducing COVID-19 transmission. Despite mass vaccination campaigns in many parts of the world, continued efforts at social distancing and face mask use remain critically important in reducing the spread of COVID-19.

Indexed as

Physical DistancingAdultAgedCOVID-19Disease Transmission, InfectiousFemaleHumansMaleMasksMiddle AgedProspective StudiesPublic HealthSARS-CoV-2United States

Identifiers

PMID34145289
PMCPMC8213701
OpenAlexW3168838372

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.