Evidence map›Paper›PMID 34145242›Full record

ArticleNature communications2021

Arginine methylation of METTL14 promotes RNA N

Xiaona Liu, Hailong Wang, Xueya Zhao, Qizhi Luo, Qingwen Wang, Kaifen Tan, Zihan Wang, Jia Jiang, Jinru Cui, Enhui Du and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Dysregulated mScience advances · 2026
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  3. WTAP-Mediated mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  4. Review
  5. Cotranslational assembly directs the biogenesis of the mProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. mScience China. Life sciences · 2025
    Article
  8. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Xiaona Liu *School of Life Sciences, University of Science and Technology of China, Hefei, P.R. China.
Hailong Wang *Kingmed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, P.R. China.
Xueya Zhao *Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Qizhi Luo *Department of Forensic Toxicology, School of Forensic Medicine, Southern Medical University, Guangzhou, P.R. China.
Qingwen WangDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Kaifen TanDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Zihan WangDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Jia JiangDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Jinru CuiDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Enhui DuDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Linjian XiaDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.
Wenyi DuSichuan MoDe Technology Co., Ltd, Chengdu, P. R. China.
Dahua ChenState Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. chendh@ioz.ac.cn.
Laixin XiaDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China. xialx@smu.edu.cn.ORCID 0000-0003-2735-9518
Shan XiaoDepartment of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China. asdfg@smu.edu.cn.ORCID 0000-0002-4012-7650
Southern Medical University · CNKingmed Diagnostics · CNUniversity of Science and Technology of China · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA N

Indexed as

AdenosineAnimalsArginineCell DifferentiationEndodermGene Expression RegulationHEK293 CellsHeLa CellsHumansMethylationMethyltransferasesMiceMouse Embryonic Stem CellsProtein-Arginine N-MethyltransferasesProtein Processing, Post-TranslationalRNA InterferenceAdenosineArginineMethyltransferasesMettl14 protein, mouseMettl3 protein, mouseN-methyladenosinePrmt1 protein, mouseProtein-Arginine N-MethyltransferasesRNA, Small Interfering

Identifiers

PMID34145242
PMCPMC8213825
OpenAlexW3167406339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.