Evidence map›Paper›PMID 34145211›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2021

A Review of Neurological Involvement in Patients with SARS-CoV-2 Infection.

Yidan Xu, Yu Zhuang, Lumei Kang

Open access · hybridAbstract readReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Stroke Risk Related to Coronavirus Disease-2019: What Have We Learned?Critical care nursing clinics of North America · 2023
    Review
  5. Psychiatric and neurological complications of long COVID.Journal of psychiatric research · 2022
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yidan XuJiangxi Key Laboratory of Experimental Animals, Nanchang University, Nanchang, Jiangxi, China (mainland).
Yu ZhuangJiangxi Key Laboratory of Experimental Animals, Nanchang University, Nanchang, Jiangxi, China (mainland).
Lumei KangJiangxi Key Laboratory of Experimental Animals, Nanchang University, Nanchang, Jiangxi, China (mainland).
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative pathogen of the recent pandemic of coronavirus disease 19 (COVID-19). As the infection spreads, there is increasing evidence of neurological and psychiatric involvement in COVID-19. Headache, impaired consciousness, and olfactory and gustatory dysfunctions are common neurological manifestations described in the literature. Studies demonstrating more specific and more severe neurological involvement such as cerebrovascular insults, encephalitis and Guillain-Barre syndrome are also emerging. Respiratory failure, a significant condition that leads to mortality in COVID-19, is hypothesized to be partly due to brainstem impairment. Notably, some of these neurological complications seem to persist long after infection. This review aims to provide an update on what is currently known about neurological involvement in patients with COVID-19 due to SARS-CoV-2 infection. In this review, we demonstrate invasion routes of SARS-CoV-2, provide evidence to support the neurotropism hypothesis of the virus, and investigate the pathological mechanisms that underlie neurological complications associated with SARS-CoV-2.

Indexed as

AgeusiaAnosmiaCOVID-19EncephalitisHeadacheHumansNervous System DiseasesNeuroimmunomodulationPandemicsPost-Acute COVID-19 SyndromeSARS-CoV-2Stroke

Identifiers

PMID34145211
PMCPMC8221270
OpenAlexW3168337929

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.