Evidence map›Paper›PMID 34145063›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

Pre-existing Simian Immunodeficiency Virus Infection Increases Expression of T Cell Markers Associated with Activation during Early

Erica C Larson, Amy Ellis-Connell, Mark A Rodgers, Alexis J Balgeman, Ryan V Moriarty, Cassaundra L Ameel, Tonilynn M Baranowski, Jaime A Tomko, Chelsea M Causgrove, Pauline Maiello and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Erica C LarsonDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA; scangaca@pitt.edu erl72@pitt.edu.ORCID 0000-0001-5025-9369
Amy Ellis-ConnellDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, WI.ORCID 0000-0002-6503-1399
Mark A RodgersDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.ORCID 0000-0001-9800-3362
Alexis J BalgemanDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, WI.
Ryan V MoriartyDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, WI.ORCID 0000-0001-7100-1906
Cassaundra L AmeelDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Tonilynn M BaranowskiDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.ORCID 0000-0002-7788-9464
Jaime A TomkoDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Chelsea M CausgroveDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Pauline MaielloDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA.ORCID 0000-0002-5188-8420
Shelby L O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, WI.ORCID 0000-0003-0183-5010
Charles A ScangaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA; scangaca@pitt.edu erl72@pitt.edu.ORCID 0000-0003-3654-5603
University of Pittsburgh · USUniversity of Wisconsin–Madison · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
The Impact of Pre-exisiting SIV on Host Immunity to M tuberculosis in MacaquesR01AI111815 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCANGA, CHARLES A. · 2015 to 2019
$3.8M
SIV/HIV dysregulation of MAIT cell function impairs anti-M.tb immunityR21AI127127 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI OCONNOR, SHELBY L · 2016 to 2017
$432k
NIAID NIH HHS R01 AI111815NIAID NIH HHS R21 AI127127NIH HHS P51 OD011106
6 · The paper itself

Abstract

Tuberculosis (TB) is the leading infectious cause of death among people living with HIV. People living with HIV are more susceptible to contracting

Indexed as

AnimalsBiomarkersCD8-Positive T-LymphocytesGranulomaMacacaMycobacterium tuberculosisSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusT-LymphocytesTuberculosisTumor Necrosis FactorsBiomarkersTumor Necrosis Factors

Identifiers

PMID34145063
PMCPMC8683577
OpenAlexW3168476854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.