Evidence map›Paper›PMID 34145005›Full record

Observational studyBMJ open2021

Prevalence and fluid management of dehydration in children without diarrhoea admitted to Kenyan hospitals: a multisite observational study.

Sylvia Omoke, Mike English, Jalemba Aluvaala, David Gathara, Ambrose Agweyu, Samuel Akech, Clinical Information Network

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sylvia OmokeHealth Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya somoke@kemri-wellcome.org.ORCID 0000-0003-1269-5519
Mike EnglishHealth Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Jalemba AluvaalaHealth Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.ORCID 0000-0002-0851-3711
David GatharaHealth Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Ambrose AgweyuHealth Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Samuel AkechHealth Services Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Clinical Information Network
Kenya Medical Research Institute · KENuffield Orthopaedic Centre · GBUniversity of Nairobi · KE

Funding

Wellcome TrustWellcome Trust 107769Wellcome Trust 207522
6 · The paper itself

Abstract

objectivesTo examine the prevalence of dehydration without diarrhoea among admitted children aged 1-59 months and to describe fluid management practices in such cases.

designA multisite observational study that used routine in-patient data collected prospectively between October 2013 and December 2018. SETTINGS: Study conducted in 13 county referral hospitals in Kenya.

participantsChildren aged 1-59 months with admission or discharge diagnosis of dehydration but had no diarrhoea as a symptom or diagnosis. Children aged <28 days and those with severe acute malnutrition were excluded.

resultsThe prevalence of dehydration in children without diarrhoea was 3.0% (2019/68 204) and comprised 15.9% (2019/12 702) of all dehydration cases. Only 55.8% (1127/2019) of affected children received either oral or intravenous fluid therapy. Where fluid treatment was given, the volumes, type of fluid, duration of fluid therapy and route of administration were similar to those used in the treatment of dehydration secondary to diarrhoea. Pneumonia (1021/2019, 50.6%) and malaria (715/2019, 35.4%) were the two most common comorbid diagnoses. Overall case fatality in the study population was 12.9% (260/2019).

conclusionSixteen per cent of children hospitalised with dehydration do not have diarrhoea but other common illnesses. Two-fifths do not receive fluid therapy; a regimen similar to that used in diarrhoeal cases is used in cases where fluid is administered. Efforts to promote compliance with guidance in routine clinical settings should recognise special circumstances where guidelines do not apply, and further studies on appropriate management for dehydration in the absence of diarrhoea are required.

Indexed as

DehydrationDiarrheaChildFluid TherapyHospitalsHumansInfantKenyaPrevalenceepidemiologypaediatric gastroenterologypaediatrics

Identifiers

PMID34145005
PMCPMC8215254
OpenAlexW3172001648

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.