Evidence map›Paper›PMID 34144976›Full record

ArticleScience advances2021

CD8

Kaiwen Li, Tiancheng Li, Zhaoyi Feng, Mei Huang, Lei Wei, Zhiyu Yan, Mark Long, Qiang Hu, Jianmin Wang, Song Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Nanotechnology Applications in Breast Cancer Immunotherapy.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  8. CD8Molecular medicine reports · 2024
    Article
  9. Oligandrin fromHeliyon · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Breast Cancer Immunity: It is TIME for the Next Chapter.Cold Spring Harbor perspectives in medicine · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Kaiwen LiCenter for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-6460-5768
Tiancheng LiCenter for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-6133-2293
Zhaoyi FengCenter for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Mei HuangCenter for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-8671-3906
Lei WeiDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.ORCID 0000-0002-1881-8666
Zhiyu YanCenter for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Mark LongDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.ORCID 0000-0003-1120-8176
Qiang HuDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.ORCID 0000-0002-4090-5539
Jianmin WangDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.ORCID 0000-0001-7527-0409
Song LiuDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Dennis C SgroiMolecular Pathology Unit, Department of Pathology, Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-4052-6659
Shadmehr DemehriCenter for Cancer Immunology and Cutaneous Biology Research Center, Department of Dermatology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. sdemehri1@mgh.harvard.edu.ORCID 0000-0002-7913-2641
Harvard University · USRoswell Park Comprehensive Cancer Center · USCenter for Cancer Research · US

Funding

Immuno-Oncology Translation Network: Data Management and Resource-Sharing Center at RPCIU24CA232979 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI HUTSON, ALAN DAVID, LIU, SONG · 2018 to 2024
$8.9M
Epithelium-derived alarmins role in breast cancer immunopreventionU01CA233097 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DEMEHRI, SHADMEHR · 2018 to 2022
$4.0M
THE MECHANISM OF TSLP ANTI-TUMOR EFFECTS IN THE SKINDP5OD021353 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI DEMEHRI, SHADMEHR · 2015 to 2019
$2.2M
The Role of Allergic Contact Dermatitis in Skin CarcinogenesisK08AR068619 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI DEMEHRI, SHADMEHR · 2015 to 2019
$753k
NCI NIH HHS U01 CA233097NCI NIH HHS U24 CA232979NIAMS NIH HHS K08 AR068619NIH HHS DP5 OD021353
6 · The paper itself

Abstract

The link between carcinogen exposure and cancer immunogenicity is unclear. Single exposure to 12-dimethylbenz[a]anthracene (DMBA) at puberty accelerated spontaneous breast carcinogenesis in mouse mammary tumor virus-polyoma middle tumor-antigen transgenic (MMTV-PyMT

Indexed as

Breast NeoplasmsLung NeoplasmsAnimalsCarcinogensCD8-Positive T-LymphocytesCell Transformation, NeoplasticFemaleHumansMiceCarcinogens

Identifiers

PMID34144976
PMCPMC8213232
OpenAlexW3167632964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.